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Involvement of MLL gene in a t(10;11)(q22;q23) and a t(8;11)(q24;q23) identified by fluorescence in situ hybridization. | LitMetric
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Involvement of MLL gene in a t(10;11)(q22;q23) and a t(8;11)(q24;q23) identified by fluorescence in situ hybridization.

A Aventín R La Starza C Martínez I Wlodarska M Boogaerts H Van den Berghe C Mecucci

Cancer Genet Cytogenet

Institute of Hematology, University of Perugia, Italy.

Published: January 1999

We describe two cases of acute myeloblastic leukemia, classified as M4 and M5 in the French-American-British nomenclature, with an 11q23 rearrangement at karyotypic analysis. The involvement of the MLL gene with two new partner loci on chromosome 10q22 and 8q24, respectively, was demonstrated by fluorescence in situ hybridization using a YAC clone B22B2L.

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http://dx.doi.org/10.1016/s0165-4608(98)00110-1DOI Listing

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