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Constructing a multi-ancestry polygenic risk score for uterine fibroids using publicly available data highlights need for inclusive genetic research.
Pac Symp Biocomput
December 2024
Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA.
Uterine leiomyomata, or fibroids, are common gynecological tumors causing pelvic and menstrual symptoms that can negatively affect quality of life and child-bearing desires. As fibroids grow, symptoms can intensify and lead to invasive treatments that are less likely to preserve fertility. Identifying individuals at highest risk for fibroids can aid in access to earlier diagnoses.
View Article and Find Full Text PDFComparison of the Effect of Auriculotherapy, a Herbal Compound (Aslagh Capsule), and Metformin on the Clinical Symptoms of Polycystic Ovary Syndrome: Randomized Clinical Trial.
Adv Biomed Res
September 2024
Department of Persian Medicine, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Article Synopsis
- Polycystic ovary syndrome (PCOS) is a common hormonal disorder in women of reproductive age, affecting 6-20% worldwide, leading to interest in alternative treatments like acupuncture and herbal remedies alongside conventional drugs.
- A study with 24 women aged 18-43 tested three treatments: auriculotherapy, Aslagh capsules, and metformin, measuring their impact on menstrual cycles and PCOS symptoms.
- Results showed all treatments reduced menstrual cycle duration, but only auriculotherapy had significant improvements in menstrual regularity and decreased excess hair growth compared to the other treatments.
Increased Human Chorionic Gonadotropin Level in a Nonsexually Active Young Female.
J Emerg Med
December 2024
The Robert Larner College of Medicine at the University of Vermont, Department of Emergency Medicine, Burlington, VT.
Background: Quantitative and qualitative human chorionic gonadotropin (hCG) tests are obtained in the emergency department (ED) to determine if a female of child-bearing age is pregnant. A positive hCG result is commonly assumed to indicate an intrauterine or other form of pregnancy. However, elevated hCG levels can also result from various other conditions, such as ovarian tumors, pituitary tumors, and thyroid disorders.
View Article and Find Full Text PDFEctopic pregnancy located at pelvic wall and liver: Two uncommon case reports from Vietnam and mini-review literature.
Int J Surg Case Rep
May 2024
Tu Du Clinical Research Unit (TD-CRU), Tu Du Hospital, Ho Chi Minh City, Viet Nam; Department of High-risk Pregnancy, Tu Du Hospital, Ho Chi Minh City, Viet Nam. Electronic address:
Introduction And Importance: Abdominal ectopic pregnancy (AEP) located at hepatic region and pelvic-wall ectopic pregnancy (EP) are rare entities, that provoking a potentially life-threatening condition. Due to insufficient data, a proper management of non-specific types remains a challenge for all gynecologists worldwide.
Case Presentation: Two child-bearing age women were hospitalized due to delayed menstruation and a urine pregnancy test was positive without a determination of intrauterine pregnancy.
Reproductive outcomes after conservative treatment in early and advanced stage MOGCTs.
Gynecol Oncol
February 2024
Department of Obstetrics and Gynecology, IRCCS San Raffaele, Milan, Italy.
Background: Malignant ovarian germ cell tumors usually occur in young women. The standard of care is fertility sparing surgery and comprehensive surgical staging followed by adjuvant chemotherapy with BEP (bleomycin, etoposide, cisplatin) if needed. The aim of this study was to analyze the reproductive outcomes after conservative treatment in patients diagnosed, treated and followed up in MITO (Multicenter Italian Trials in Ovarian Cancer) centers.
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