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Neuroimmune axis: Linking environmental factors to pancreatic β-cell dysfunction in Diabetes.
Brain Behav Immun Health
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Laboratory of Immuno-Endocrinology, Diabetes and Metabolism, Instituto de Investigaciones en Medicina Traslacional (IIMT), CONICET-Universidad Austral, Pilar, Argentina.
Pancreatic β-cells are specialized in secreting insulin in response to circulating nutrients, mainly glucose. Diabetes is one of the most prevalent endocrine-metabolic diseases characterized by an imbalance in glucose homeostasis, which result mainly from lack of insulin production (type 1 diabetes) or insufficient insulin and peripheral insulin resistance (type 2 diabetes), both influenced by genetic and environmental components. Pancreatic β-cell dysfunction and islet inflammation are common characteristics of both types of the disease.
View Article and Find Full Text PDFSuperconductivity from Domain Wall Fluctuations in Sliding Ferroelectrics.
Phys Rev Lett
December 2024
Materials Science Division, Argonne National Laboratory, Lemont, Illinois 60439, USA.
Bilayers of two-dimensional van der Waals materials that lack an inversion center can show a novel form of ferroelectricity, where certain stacking arrangements of the two layers lead to an interlayer polarization. Under an external out-of-plane electric field, a relative sliding between the two layers can occur, accompanied by an interlayer charge transfer and a ferroelectric switching. We show that the domain walls that mediate ferroelectric switching are a locus of strong attractive interactions between electrons.
View Article and Find Full Text PDFLack of up-to-date studies and data conversion may lead to biased results: a response to Wang et al.
Crit Care
December 2024
Médecine Intensive Et Réanimation, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, University of Paris, Paris, France.
Defining an Undergraduate Radiation Oncology Microclerkship Using the Delphi Method.
Pract Radiat Oncol
December 2024
Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
Purpose: Many medical students in the US lack formal exposure to radiation oncology (RO). In contrast to multi-week electives, microclerkships, defined here as brief (<1 week) observerships, could provide exposure to RO. The primary objective of this study was to establish expert consensus for the duration, curriculum, target audience, and goals/objectives of an RO microclerkship.
View Article and Find Full Text PDFLateral abdominal wall hernias after coughing: a single center experience.
Hernia
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Department of Surgery, Cleveland Clinic Center for Abdominal Core Health Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
Purpose: Forceful coughing is assumed to be an uncommon etiology for lateral abdominal wall hernias. The literature regarding this topic is very limited and there is a lack of consensus in management, both operative and non-operative. We aim to report our center's experience in repair of lateral abdominal wall hernias secondary to vigorous coughing.
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