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The potential of the i-TED Compton camera array for real-time boron imaging and determination during treatments in Boron Neutron Capture Therapy.
Appl Radiat Isot
December 2024
Instituto de Física Corpuscular (CSIC-Universidad de Valencia), Valencia, Spain.
This paper explores the adaptation and application of i-TED Compton imagers for real-time dosimetry in Boron Neutron Capture Therapy (BNCT). The i-TED array, previously utilized in nuclear astrophysics experiments at CERN, is being optimized for detecting and imaging 478 keV gamma-rays, critical for accurate BNCT dosimetry. Detailed Monte Carlo simulations were used to optimize the i-TED detector configuration and enhance its performance in the challenging radiation environment typical of BNCT.
View Article and Find Full Text PDFPulse Shape Discrimination of n/γ in Liquid Scintillator at PMT Nonlinear Region Using Artificial Neural Network Technique.
Sensors (Basel)
December 2024
Center for Precision Neutrino Research, Department of Physics, Chonnam National University, Gwangju 61186, Republic of Korea.
Reactor-emitted electron antineutrinos can be detected via the inverse beta decay reaction, which produces a characteristic signal: a two-fold coincidence between a prompt positron event and a delayed neutron capture event within a specific time frame. While liquid scintillators are widely used for detecting neutrinos reacting with matter, detection is difficult because of the low interaction of neutrinos. In particular, it is important to distinguish between neutron (n) and gamma (γ) signals.
View Article and Find Full Text PDFDevelopment of anticoincidence detector specializing in small-angle Compton scattering gamma rays for boron neutron capture therapy.
Appl Radiat Isot
December 2024
Division of Quantum and Radiation Engineering, Graduate School of Engineering, Osaka Metropolitan University, 1-2 Gakuen-cho, Naka-ku, Sakai, Osaka, 599-8570, Japan.
A novel anticoincidence detector is proposed for the measurement of 478 keV gamma radiation for evaluation of boron neutron capture therapy. The Compton continuum around the target photopeak position is effectively suppressed by measuring only the Compton gamma rays scattered at small angles from the primary detector. A numerical evaluation using Monte Carlo simulations estimated an 80% reduction in counts, and the developed prototype detector showed 4% suppression of the Compton continuum of cobalt-60 gamma rays.
View Article and Find Full Text PDFDose optimization of extended collimators in boron neutron capture therapy.
Biomed Phys Eng Express
December 2024
Shandong Key Laboratory of Neutron Science and Technology, International Academy of Neutron Science, Qingdao 266199, People's Republic of China.
In this paper, we propose the design of extending collimators aimed at reducing the radiation dose received by patients with normal tissues and protecting organs at risk in Boron Neutron Capture Therapy (BNCT). Three types of extended collimators are studied: Type 1, which is a traditional design; Type 2, which is built upon Type 1 by incorporating additional polyethylene material containing lithium fluoride (PE(LiF)); Type 3, which adds lead (Pb) to Type 1. We evaluated the dose distribution characteristics of the above-extended collimators using Monte Carlo methods simulations under different configurations: in air, in a homogeneous phantom, and a humanoid phantom model.
View Article and Find Full Text PDFCharacterization of acrylic phantom for use in quality assurance of BNCT beam output procedure.
J Radiat Res
November 2024
Particle Radiation Oncology Research Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2, Asashiro-Nishi, Kumatori-cho, Sennan-gun, Osaka 590-0494, Japan.
The accelerator-based boron neutron capture therapy (BNCT) system has been approved for specific cases covered by health insurance, and clinical trials for new cases in Japan are currently being conducted on other systems. Owing to the progress of accelerator-based BNCT, the operation of medical physics must be rendered more efficient. A water phantom is used for the quality assurance (QA) of the BNCT beam output procedure; however, a solid phantom is preferred for routine QA because of its ease of use.
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