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Subgroups of cognitive impairments in schizophrenia characterized by executive function and their morphological features: a latent profile analysis study.
BMC Med
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Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Background: The heterogeneity of cognitive impairments in schizophrenia has been widely observed. However, reliable cognitive boundaries to differentiate the subgroups remain elusive. The key challenge for cognitive subtyping is applying an integrated and standardized cognitive assessment and understanding the subgroup-specific neurobiological mechanisms.
View Article and Find Full Text PDFExploring artificial intelligence for differentiating early syphilis from other skin lesions: a pilot study.
BMC Infect Dis
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Melbourne Sexual Health Centre, Alfred Health, Melbourne, VIC, Australia.
Background: Early diagnosis of syphilis is vital for its effective control. This study aimed to develop an Artificial Intelligence (AI) diagnostic model based on radiomics technology to distinguish early syphilis from other clinical skin lesions.
Methods: The study collected 260 images of skin lesions caused by various skin infections, including 115 syphilis and 145 other infection types.
Development and validation of a risk prediction model related to inflammatory and nutritional indexes for postoperative pulmonary infection after radical colorectal cancer surgery.
BMJ Open
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Department of Nutrition and Food Hygiene, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China
Objective: To develop and validate a risk prediction model related to inflammatory and nutritional indexes for postoperative pulmonary infection (POI) after radical colorectal cancer (CRC) surgery.
Design: Cross-sectional study.
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Unraveling the pathogenesis of bone marrow hematopoietic injury and the therapeutic potential of natural products.
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TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province. Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. Electronic address:
Bone marrow hematopoietic injury encompasses a range of pathological conditions that disrupt the normal function of the hematopoietic system, primarily through the impaired production and differentiation of bone marrow hematopoietic cells. Key pathogenic mechanisms include aging, radiation damage, chemical induction, infection and inflammation, and cross-talk with non-hematopoietic diseases. These pathological factors often lead to myelosuppression and myeloid skewing.
View Article and Find Full Text PDFIn situ swelling of low-friction, high load-bearing self-bending bilayer hydrogels inspired by articular cartilage.
Biomed Mater
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School of Advanced Manufacturing, Nanchang University - Qianhu Campus, Nanchang, Jiangxi, China, Nanchang, --- Select One ---, 330031, CHINA.
The articular cartilage is characterized by its gradient hierarchical structure, which exhibits excellent lubrication and robust load-bearing properties. However, its inherent difficulty in self-repair after damage presents numerous formidable challenges for cartilage repair. Inspired by the unique structure of articular cartilage, a biomimetic bilayer hydrogel composed of PAM (polyacrylamide) and PAM/SA (sodium alginate) is prepared using a two-step in-situ swelling method.
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