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Detailed cytogenetic analysis of three duck species (the northern pintail, mallard, and common goldeneye) and karyotype evolution in the family Anatidae (Anseriformes, Aves).
Vavilovskii Zhurnal Genet Selektsii
November 2024
Institute of Molecular and Cellular Biology of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Galliformes and Anseriformes are two branches of the Galloanserae group, basal to other Neognathae. In contrast to Galliformes, Anseriformes have not been thoroughly researched by cytogenetic methods. This report is focused on representatives of Anseriformes and the evolution of their chromosome sets.
View Article and Find Full Text PDFFrom Mild Cases to Critical Cases of COVID-19: The Role of Genes in Inflammasome and Mitochondrial Dynamics.
Iran J Allergy Asthma Immunol
July 2024
Allied Medical Science Faculty, Kashan University of Medical Science School, Kashan, Iran.
The coronavirus disease 2019 (CVOID-19) has varied clinical manifestations including mild to severe acute respiratory symptoms. Inflammasome complex and mitochondria play an important role in initiating inflammatory responses and could potentially be affected by this infection. To study the inflammasome and mitochondrial fission and fusion gene expression levels in COVID-19 patients, we designed this experiment.
View Article and Find Full Text PDFTat-Beclin-1 Ameliorates Memory by Improving Neuronal Cytoarchitecture and Mitigating Mitochondrial Dysfunction in Scopolamine-Induced Amnesic Male Mice.
ACS Pharmacol Transl Sci
November 2024
Biochemistry and Molecular Biology Laboratory, Centre of Advanced Study, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi 221 005, India.
Mitophagy, the targeted breakdown of damaged mitochondria, plays a vital role in maintaining cellular homeostasis. As impairment of mitophagy leads to neurodegeneration and memory decline, the current study explores the therapeutic potential of an autophagy inducer Tat-Beclin-1 during scopolamine-induced amnesia. Tat-Beclin-1 improved contextual and recognition memory and also mitochondrial ultrastructure by restoring mitochondrial length and area and reducing the number of fragmented mitochondria.
View Article and Find Full Text PDFMitochondrial fission controls astrocyte morphogenesis and organization in the cortex.
bioRxiv
October 2024
The Department of Cell Biology, Duke University Medical Center, Durham, NC, USA.
Article Synopsis
- * The study shows that a protein called Drp1 is essential for mitochondrial fission, which helps maintain the structure and organization of astrocytes during postnatal brain development.
- * Loss of Drp1 leads to abnormal astrocyte shapes and increased reactivity, along with a decrease in a crucial protein (Connexin 43) that affects astrocyte communication, highlighting the importance of mitochondria in brain health.
Development of Neural Network Potentials for Studying Chemical Behaviors of La/Nd Ions in Molten LiCl-KCl-CsCl in Combination with Raman Spectroscopy.
J Phys Chem B
November 2024
Laboratory of Nuclear Energy Chemistry, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China.
The chemistry of molten salts has attracted great research interest owing to their wide applications in diverse fields. In the pyrochemical reprocessing of spent nuclear fuel or molten salt nuclear reactors, lanthanide elements as the principal fission products bring about changes in the composition and properties of molten salts. Herein, we report a comprehensive study on the coordination chemistry of the representative trivalent lanthanide ions (La/Nd) in LiCl-KCl-CsCl using a multiscale strategy combining Raman spectroscopy, deep learning, and large-scale molecular dynamics (MD) simulations.
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