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Defining the Zone of Acute Peripheral Nerve Injury Using Fluorescence Lifetime Imaging in a Crush Injury Sheep Model.
J Hand Surg Am
January 2025
Hand and Upper Extremity Division of Plastic and Reconstructive Surgery, University of California Davis, Sacramento, CA.
Purpose: Current technologies to define the zone of acute peripheral nerve injury intraoperatively are limited by surgical experience, time, cumbersome electrodiagnostic equipment, and interpreter reliability. In this pilot study, we evaluated a real-time, label-free optical technique for intraoperative nerve injury imaging. We hypothesize that fluorescence lifetime imaging (FLIm) will detect a difference between the time-resolved fluorescence signatures for acute crush injuries versus uninjured segments of peripheral nerves in sheep.
View Article and Find Full Text PDFIsolation and identification of the causal agent of gummy stem blight disease in Cucumis sativus caused by a bacterial pathogen in China.
Sci Rep
January 2025
College of Plant Protection, Biocontrol Engineering Laboratory of Crop Diseases and Pests of Gansu Province, Gansu Agricultural University, Lanzhou, 730070, China.
Recently, a new bacterial disease was detected on cucumber stalks. In order to study the pathogenesis of this disease, the pathogenic bacteria were isolated and identified on the basis of morphological and molecular characteristics, and further analyzed for pathogenicity and antagonistic evaluation. Pathogenicity analysis showed that HlJ-3 caused melting decay and cracking in cucumber stems, and the strain reisolated from re-infected cucumber stalks was morphologically identical to HlJ-3 colonies, which is consistent with the Koch's postulates.
View Article and Find Full Text PDFIncongruent virtual reality cycling exercise demonstrates a role of perceived effort in cardiovascular control.
J Physiol
January 2025
Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, United Kingdom.
In this study we have used a highly immersive virtual reality (VR) cycling environment where incongruence between virtual hill gradient (created by visual gradient and bike tilt angle) and actual workload (pedalling resistance) can experimentally manipulate perception of exercise effort. This therefore may provide a method to examine the role of effort perception in cardiorespiratory control during exercise. Twelve healthy untrained participants (7 men, age 26 ± 5 years) were studied during five visits.
View Article and Find Full Text PDFCircadian clock communication during homeostasis and ageing.
Nat Rev Mol Cell Biol
January 2025
Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Maintaining homeostasis is essential for continued health, and the progressive decay of homeostatic processes is a hallmark of ageing. Daily environmental rhythms threaten homeostasis, and circadian clocks have evolved to execute physiological processes in a manner that anticipates, and thus mitigates, their effects on the organism. Clocks are active in almost all cell types; their rhythmicity and functional output are determined by a combination of tissue-intrinsic and systemic inputs.
View Article and Find Full Text PDFNon-consumptive value of hilsa fishery restoration in West Bengal, India: An application of contingent valuation method.
J Environ Manage
January 2025
ICAR-Central Inland Fisheries Research Institute, Barrackpore, Kolkata, 700 120, India.
The study focuses on the socio-cultural importance of hilsa fishery in West Bengal, which extends beyond mere sustenance, symbolising heritage, identity, and community spirit, particularly in South 24 Parganas district. As the state fish and a crucial livelihood source for many fishers, grave concerns have recently been flagged due to reduced catches and increased prices, highlighting the need for restoration. This study seeks to measure the non-consumptive value of hilsa fishery by involving 200 participants, 100 fishers and 100 consumers, utilising the Contingent Valuation Method (CVM) with a payment card.
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