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http://dx.doi.org/10.1103/physreve.51.2363 | DOI Listing |
Proc Nutr Soc
January 2025
Department of Nutritional Sciences, Faculty of Health and Medical Science, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom.
The potential influence of the timing of eating on body weight regulation in humans has attracted substantial research interest. This review aims to critically evaluate the evidence on timed eating for weight loss, considering energetic and behavioural components to the timing of eating in humans. It has been hypothesised that timed eating interventions may alter energy balance in favour of weight loss by enhancing energy expenditure, specifically the thermic effect of food.
View Article and Find Full Text PDFBehav Brain Res
January 2025
Division of Biotechnology, School of Life Sciences, Manipal Academy of Higher Education, Manipal- 576104, India.
Whilst the world sees the tremendous growth of mobile phone technology, radiofrequency electromagnetic radiation (RF-EMR) induced possible health effects have emerged as a topic of recent day debate. The current study is designed to test the hypothesis that chronic 900MHz radiation exposure would potentially dysregulate the stress response system (HPA axis) in vivo, via, its non-thermal mechanisms, leading to alterations in the microarchitecture of the adrenal gland, vulnerable brain regions such as the hippocampus which may results in altered behaviours in rats. Male albino Wistar rats aged four weeks, weighing 50-60g were subjected to 900MHz radiation from a cellphone for four weeks at a rate of one hour per day.
View Article and Find Full Text PDFBackground: The associations between work-history trajectories and cognitive impairment among older adults were unknown. We investigated the association between work-history patterns and cognitive trajectories in later life.
Method: We conducted the study by using four regular waves and Life History survey in the Harmonized Dataset of the China Health and Retirement Longitudinal Study (CHARLS), included 5511 participants (47.
Alzheimers Dement
December 2024
University of Kentucky College of Medicine, Sanders-Brown Center on Aging, Lexington, KY, USA.
Background: Single cell RNA sequencing has defined multiple transcription states of microglia in the context of AD neuropathology. Growing appreciating for several of these disease-associated phenotypes are linked with acquisition of altered metabolism, conceptually known as immunometabolism. Despite increasing knowledge in microglial heterogeneity, relatively little is known regarding the spatial distribution of these phenotypes in the context of pathology proximity.
View Article and Find Full Text PDFBackground: Measures of cardiovascular health have long been associated with brain health. For example, aerobic capacity (VO2max) is associated with preservation of functional and structural brain integrity in later life. Recent work has highlighted the utility of relative brain age (RBA; the age-corrected difference between a brain's chronological and estimated biological ages) to examine the rate of biological brain aging.
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