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Novel Self-Powered Sensitive X-Ray Detection Crystal BiMoWO with Effective Functional Motif Coupling in a Quasi-2D Perovskite Structure.
Small
January 2025
State Key Laboratory of Crystal Materials, Shandong University, 27th South Shanda Road, Jinan, 250100, China.
The demand for medical imaging with reduced patient dosage and higher resolution is growing, driving the need for advanced X-ray detection technologies. This paper proposes a design paradigm for X-ray detection semiconductors by coupling constituent motifs through crystal structure engineering. The study introduces a strongly anisotropic Aurivillius-type quasi-2D perovskite structure, combining [BiO] groups with stereochemically active lone pair electrons (SCALPEs) and [W/MoO] anionic groups, enabling enhanced X-ray Compton scattering and self-powered capabilities through local electric field ordering.
View Article and Find Full Text PDFChained occurrences of early afterdepolarizations may create a directional triggered activity to initiate reentrant ventricular tachyarrhythmias.
Comput Methods Programs Biomed
January 2025
Department of Physiology II, Kanazawa Medical University, Uchinada 920-0293, Japan. Electronic address:
Background And Objective: It has been believed that polymorphic ventricular tachycardia (VT) such as torsades de pointes (TdP) seen in patients with long QT syndromes is triggered by creating early afterdepolarization (EAD)-mediated triggered activity (TA). Although the mechanisms creating the TA have been studied intensively, characteristics of the arrhythmogenic (torsadogenic) substrates that link EAD developments to TA formation are still not well understood.
Methods: Computer simulations of excitation propagation in a homogenous two-dimensional ventricular tissue with an anisotropic conduction property were performed to characterize torsadogenic substrates that potentially form TA.
Range and accuracy of in-plane anisotropic thermal conductivity measurement using the laser-based Ångstrom method.
Rev Sci Instrum
January 2025
Birck Nanotechnology Center and the School of Mechanical Engineering, Purdue University, West Lafayette, Indiana 47907, USA.
High heat fluxes in electronic devices must be effectively dissipated to prevent local hotspots, which are critical for long-term device reliability. In particular, advanced semiconductor packaging trends toward thin form factor products increase the need for understanding and improving in-plane conduction heat spreading in anisotropic materials. The 2D laser-based Ångstrom method, an extension of traditional Ångstrom and lock-in thermography techniques, measures in-plane thermal properties of anisotropic sheet-like materials.
View Article and Find Full Text PDFHow cells align to structured collagen fibrils: a hybrid cellular Potts and molecular dynamics model with dynamic mechanosensitive focal adhesions.
Front Cell Dev Biol
January 2025
Mathematical Institute, Faculty of Science, Leiden University, Leiden, Netherlands.
Many mammalian cells, including endothelial cells and fibroblasts, align and elongate along the orientation of extracellular matrix (ECM) fibers in a gel when cultured . During cell elongation, clusters of focal adhesions (FAs) form near the poles of the elongating cells. FAs are mechanosensitive clusters of adhesions that grow under mechanical tension exerted by the cells' pulling on the ECM and shrink when the tension is released.
View Article and Find Full Text PDFGraded porous scaffold mediates internal fluidic environment for 3D in vitro mechanobiology.
Comput Biol Med
January 2025
Department of Biomedical Engineering, Faculty of Science and Engineering, Swansea University, Swansea, United Kingdom; Zienkiewicz Institute for Modelling Data and AI, Swansea University, Swansea, United Kingdom. Electronic address:
Most cell types are mechanosensitive, their activities such as differentiation, proliferation and apoptosis, can be influenced by the mechanical environment through mechanical stimulation. In three dimensional (3D) mechanobiological in vitro studies, the porous structure of scaffold controls the local mechanical environment that applied to cells. Many previous studies have focused on the topological design of homogeneous scaffold struts.
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