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Mechanical Cell Interactions on Curved Interfaces.
Bull Math Biol
January 2025
School of Mathematical Sciences, Queensland University of Technology (QUT), Brisbane, Australia.
We propose a simple mathematical model to describe the mechanical relaxation of cells within a curved epithelial tissue layer represented by an arbitrary curve in two-dimensional space. This model generalises previous one-dimensional models of flat epithelia to investigate the influence of curvature for mechanical relaxation. We represent the mechanics of a cell body either by straight springs, or by curved springs that follow the curve's shape.
View Article and Find Full Text PDFTuning the mechanical properties of alginate dialdehyde-gelatin (ADA-GEL) bioinks for bioprinting approaches by varying the degree of oxidation.
J Mech Behav Biomed Mater
December 2024
Institute of Continuum Mechanics and Biomechanics, Department of Mechanical Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg, 90762 Fürth, Germany. Electronic address:
Extrusion-based 3D bioprinting is one of the most promising and widely used technologies in bioprinting. However, the development of bioprintable, biocompatible bioinks with tailored mechanical and biological properties remains a major challenge in this field. Alginate dialdehyde-gelatin (ADA-GEL) hydrogels face these difficulties and enable to tune the mechanical properties depending on the degree of oxidation (% DO) of ADA.
View Article and Find Full Text PDFThe importance of shear on the collective charge transport in CDWs revealed by an XFEL source.
Sci Adv
January 2025
Laboratoire de Physique des Solides, Université Paris-Saclay, CNRS, 91405 Orsay, France.
Charge transport in materials has an impact on a wide range of devices based on semiconductor, battery, or superconductor technology. Charge transport in sliding charge density waves (CDW) differs from all others in that the atomic lattice is directly involved in the transport process. To obtain an overall picture of the structural changes associated to the collective transport, the large coherent x-ray beam generated by an x-ray free-electron laser (XFEL) source was used.
View Article and Find Full Text PDFMeasuring the biomechanical properties of cell-derived fibronectin fibrils.
Biomech Model Mechanobiol
December 2024
Department of Biomedical Engineering, Virginia Commonwealth University, 401 W. Main St., Richmond, VA, 23284, USA.
Article Synopsis
- FN (fibronectin) fibrils are crucial for processes like embryonic development and wound healing, but their mechanical properties are not well understood.
- A new system allows for the measurement of cell-derived FN fibrils, revealing three types of elasticity (linear, strain-hardening, and nonlinear) and showing that fibril behavior changes with repeated stretching.
- The average elasticity of these fibrils is about 8 MPa, and they display time-dependent viscoelastic behavior, which could deepen our knowledge of cellular mechanics in development and fibrotic diseases.
Open-World Games' Affordance of Cognitive Escapism, Relaxation, and Mental Well-Being Among Postgraduate Students: Mixed Methods Study.
J Med Internet Res
December 2024
Imperial College Business School, Imperial College London, London, United Kingdom.
Background: Open-world games, characterized by their expansive and interactive environments, may offer unique cognitive escapism opportunities, potentially leading to relaxation and enhanced well-being. These games, such as "The Legend of Zelda: Breath of the Wild" and "The Legend of Zelda: Tears of the Kingdom," allow players to experience a sense of freedom and autonomy, which can reduce stress and improve mental health. While previous research has examined the general impact of video games on mental well-being, specific studies on the effects of open-world games among postgraduate students are limited.
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