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Achieving the Needed Correction in Vertebral Body Tethering: The Relationship Between Preoperative Flexibility, Intraoperative Correction, and First Erect Imaging.
J Pediatr Orthop
December 2024
Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN.
Background: Vertebral body tethering (VBT) is a nonfusion surgical treatment for scoliosis. Recent data have shown that intraoperative correction is critical for successful curve correction over time. This study aims to evaluate the relationship between preoperative, intraoperative, and postoperative correction.
View Article and Find Full Text PDFDirect Induction of Buprenorphine Extended-Release: A Case Report.
J Addict Med
December 2024
From the Integrated Psychiatry, Pain, and Addiction Service, Vancouver General Hospital, Vancouver, British Columbia, Canada (PA, JSHW, JM, MN, VWL, MJI, NM); Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada (PA, MN, VWL, MJI, NM); Addictions and Concurrent Disorders Research Group, Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada (JSHW, RMK); Substance Use Response and Facilitation Service, BC Children's Hospital, Provincial Health Services Authority, Vancouver, British Columbia, Canada (MJI); BC Mental Health & Substance Use Services, Provincial Health Services Authority, Vancouver, British Columbia, Canada (NM); Bridge, Public Health Institute, Oakland, CA (AAH); Department of Emergency Medicine, Highland General Hospital-Alameda Health System, Oakland, CA (AAH); Department of Emergency Medicine, University of California, San Francisco, CA (AAH); The C4 Foundation, Coronado, CA (RM); British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada (JSGM); Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada (JSGM); and Pharmacokinetics Modeling and Simulation Laboratory, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada (ARM).
Buprenorphine has superior safety in opioid use disorder compared with alternatives due to its action as a partial opioid agonist, which limits its ability to cause respiratory depression. There is a risk of precipitated opioid withdrawal after buprenorphine exposure in someone using full opioid agonists. Buprenorphine induction strategies that avoid precipitated withdrawal remain a crucial component for starting buprenorphine in individuals actively using opioids.
View Article and Find Full Text PDFObservational comparison of fatigue and sleep disturbance after traumatic injury, in those with and without concomitant mild traumatic brain injury.
Am J Phys Med Rehabil
December 2024
Melbourne School of Psychological Sciences, The University of Melbourne, Victoria 3010, Australia.
Objective: Fatigue and subjective sleep disturbance are elevated after mild traumatic brain injury (mTBI), raising the question of whether mTBI-specific factors contribute to the experience of fatigue and subjective sleep disturbance after mTBI.
Design: 110 premorbidly healthy individuals who had suffered a traumatic injury during an accident approximately 8 weeks prior were examined and assessed with subjective measures of fatigue and sleep disturbance, psychological distress and pain.
Results: Individuals with a traumatic injury reported significant elevations in most fatigue and all subjective sleep disruption components compared to community-based control participants (n = 45).
Reproducibility and repeatability of 18F-(2S, 4R)-4-fluoroglutamine PET imaging in preclinical oncology models.
PLoS One
January 2025
Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, United States of America.
Introduction: Measurement of repeatability and reproducibility (R&R) is necessary to realize the full potential of positron emission tomography (PET). Several studies have evaluated the reproducibility of PET using 18F-FDG, the most common PET tracer used in oncology, but similar studies using other PET tracers are scarce. Even fewer assess agreement and R&R with statistical methods designed explicitly for the task.
View Article and Find Full Text PDFFrequencies and functions of vocalizations and gestures in the second year of life.
PLoS One
January 2025
Origin of Language Laboratories, School of Communication Sciences and Disorders, University of Memphis, Memphis, Tennessee, United States of America.
Speculations on the evolution of language have invoked comparisons across human and non-human primate communication. While there is widespread support for the claim that gesture plays a central, perhaps a predominant role in early language development and that gesture played the foundational role in language evolution, much empirical information does not accord with the gestural claims. The present study follows up on our prior work that challenged the gestural theory of language development with longitudinal data showing early speech-like vocalizations occurred more than 5 times as often as gestures in the first year of life.
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