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The magnitude of the natural killer (NK) cell response contributes to the achievement of treatment-free remission (TFR) in patients with chronic myeloid leukemia (CML) and is regulated by the interaction between killer immunoglobulin-like receptors (KIRs) on NK cells and human leukocyte antigen (HLA) class I molecules on target cells. The abundant combination between and through genetic polymorphisms determines the functional diversity of NK cells. We previously reported that status is associated with achievement of TFR by reflecting NK cell potential.
View Article and Find Full Text PDFPhotothermal Catalytic Recycling of Polyester Over Magnetic Ni-MnO Nanocatalyst.
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December 2024
School of Materials and Energy, Guangdong University of Technology, Guangzhou, 510006, China.
The solar-driven catalytic recycling of plastics has recently emerged as a new frontier in industry. Nevertheless, its large-scale application requires the catalysts being capable of the strong absorption of visible and near-infrared light, strengthened photothermal efficiency, high activity and selective toward target product, enhanced stability, as well as easy separation from the products. In this work, magnetic Ni-MnO nanocatalyst (MN/C) is synthesized via the pyrolysis of metal-organic framework (MOF) for the photothermal catalytic recycling of polyethylene terephthalate (PET) to bis(2-hydroxyethyl) terephthalate (BHET).
View Article and Find Full Text PDFEvaluation of Probiotic Potential and Functional Properties of Strains Isolated from Dhan, Traditional Algerian Goat Milk Butter.
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November 2024
Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia (UKM), Bangi 43600, Malaysia.
Goat milk butter, locally known as "Dhan", from the Sfisfa region of Algeria, holds significant cultural and economic value. This study investigates the probiotic properties of lactic acid bacteria (LAB) present in Dhan, focusing particularly on strains. Molecular identification using 16S rRNA revealed a dominance of and , forming a substantial part of the bacterial profile.
View Article and Find Full Text PDFA comprehensive investigation of PRMT5 in the prognosis and ion channel features of lung cancer.
Front Oncol
November 2024
Department of Thoracic Surgery, The Second Affiliated Hospital, Air Force Medical University, Xi'an, China.
The increasing incidence and mortality associated with lung cancer (LC) is a significant global health challenge. The underlying mechanisms contributing to LC remain inadequately understood. However, emerging evidence suggests that the epigenetic modifier protein arginine methyltransferase 5 (PRMT5) plays a complex role in various cellular processes, including DNA repair, gene transcription, and alternative splicing, through its function in catalyzing the symmetric dimethylation of both histone and non-histone proteins.
View Article and Find Full Text PDFTerpenoids as principal bioactive compound of essential oils: enhancing synergistic efficacy with conventional antibiotics.
Front Cell Infect Microbiol
December 2024
Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)., Shenzhen, Guangdong, China.
Background: The rise of antibiotic resistance imposes the search for novel antimicrobial strategies as natural products or its combination with antibiotics. This study investigates the synergistic effects of terpenoids from () essential oil in combination with antibiotics against () and (). The aims were to evaluate the antimicrobial efficacy, analyze functional group modifications and assess molecular interaction.
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