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http://dx.doi.org/10.1103/physrevd.31.2732 | DOI Listing |
Vaccines (Basel)
November 2024
Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale", 64100 Teramo, Italy.
Lumpy skin disease virus ( family- genus) is the aetiological agent of LSD, a disease primarily transmitted by hematophagous biting, affecting principally cattle. Currently, only live attenuated vaccines are commercially available, but their use is limited to endemic areas. There is a need for safer vaccines, especially in LSD-free countries.
View Article and Find Full Text PDFPharmaceutics
December 2024
National Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.
Microneedles (MNs), composed of multiple micron-scale needle-like structures attached to a base, offer a minimally invasive approach for transdermal drug delivery by penetrating the stratum corneum and delivering therapeutic agents directly to the epidermis or dermis. Hydrogel microneedles (HMNs) stand out among various MN types due to their excellent biocompatibility, high drug-loading capacity, and tunable drug-release properties. This review systematically examines the matrix materials and fabrication methods of HMN systems, highlighting advancements in natural and synthetic polymers, and explores their applications in treating conditions such as wound healing, hair loss, cardiovascular diseases, and cancer.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
Department of Autonomous Vehicle System Engineering, Chungnam National University, Daejeon 34134, Republic of Korea.
Among 3D printing technologies, fused filament fabrication (FFF) is a fast, simple, and low-cost technology that is being explored in a variety of industries. FFF produces composites using thermoplastic filaments, limiting the applicability of welding. Therefore, mechanical fastening is required to join FFF composites with metals or dissimilar materials.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology (JAIST), 1-1 Asahidai, Nomi 923-1292, Japan.
Polybenzimidazole (PBI) is a high-performance polymer known for its excellent thermal stability, mechanical strength, and chemical resistance, attributes that are derived from its unique structure comprising repeated benzene and imidazole rings. However, limitations such as relatively low thermal stability and moisture sensitivity restrict its application as a super engineering plastic. In this study, amide groups are incorporated into the PBI backbone to synthesize the copolymer poly(BI--A), effecting a structural modification at the molecular level.
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December 2024
Soete Laboratory, Faculty of Engineering and Architecture, Ghent University, B-9052 Ghent, Belgium.
Epoxy resins have exhibited exceptional performance in engineering applications, particularly as a replacement for traditional mechanical joints in adhesive bonding. This study evaluates the suitability of two innovative adhesives, SikaPower-1511 and SikaPower-1548, in various graded configurations. The thermal curing behavior of the adhesives was analyzed using differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR).
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