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Basic Science and Pathogenesis.
Alzheimers Dement
December 2024
Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.
Background: Common and rare variants in SORL1 have been associated with increased risk of Alzheimer's disease (AD). Since 2019, we have run an international collaborative research initiative to ascertain a Peruvian cohort for Alzheimer's disease and other related dementias for genetic studies (PeADI).
Method: A Peruvian family (4 AD cases and two mild cognitive impairment (MCI) cases) was recruited through the PeADI study.
Search for Fractionally Charged Particles with CUORE.
Phys Rev Lett
December 2024
Dipartimento di Fisica e Astronomia, Alma Mater Studiorum-Università di Bologna, Bologna I-40127, Italy.
The Cryogenic Underground Observatory for Rare Events (CUORE) is a detector array comprised by 988 5 cm×5 cm×5 cm TeO_{2} crystals held below 20 mK, primarily searching for neutrinoless double-beta decay in ^{130}Te. Unprecedented in size among cryogenic calorimetric experiments, CUORE provides a promising setting for the study of exotic throughgoing particles. Using the first tonne year of CUORE's exposure, we perform a search for hypothesized fractionally charged particles (FCPs), which are well-motivated by various standard model extensions and would have suppressed interactions with matter.
View Article and Find Full Text PDFFirst report of tobacco root rot caused by in Guangdong of China.
Plant Dis
December 2024
Xuchang, China;
Tobacco ( L.) is an economically important crop in China. In April 2024, field tobacco (cv.
View Article and Find Full Text PDFPhytic acid promotes the oxidative stress tolerance of Meyerozyma (Pichia) caribbica enhancing its efficacy against natural decay and retaining the quality of table grapes.
Plant Physiol Biochem
December 2024
School of Food and Biological Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013, Jiangsu, PR China. Electronic address:
Article Synopsis
- The yeast Pichia caribbica from the Meyerozyma guilliermondii species complex shows diverse abilities that help it adapt and survive in various environments.
- The study explored how phytic acid (PA) can improve P. caribbica's effectiveness in protecting table grapes from decay and preserving their quality, with findings indicating that PA enhances yeast growth and biofilm formation.
- Treatment with PA not only increased antioxidant enzyme activity in P. caribbica but also led to better control of grape decay during storage, demonstrating potential for sustainable postharvest solutions that consumers found appealing based on improved grape quality.
Spatiotemporal distributions, co-occurrence networks, and assembly mechanisms of the bacterial community in sediments of the Yangtze River: comprehensive insights into abundant and rare taxa.
Front Microbiol
December 2024
College of Water Sciences, Beijing Normal University, Beijing, China.
Sediments are key reservoirs for rare bacterial biospheres that provide broad ecological services and resilience in riverine ecosystems. Compared with planktons, there is a lack of knowledge regarding the ecological differences between abundant and rare taxa in benthic bacteria along a large river. Here, we offer comprehensive insights into the spatiotemporal distributions, co-occurrence networks, and assembly processes of three divided categories namely always rare taxa (ART), conditionally rare taxa (CRT), and conditionally rare and abundant taxa (CRAT) in sediments covering a distance of 4,300 km in the Yangtze River.
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