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Exploring the binding mode of BBA protein anchored on defective graphene and evaluating the biocompatibility of two types of graphene with λ-repressor protein.
Colloids Surf B Biointerfaces
January 2025
College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China. Electronic address:
Since defects in nanomaterials are inevitable during experimental manipulation, investigating the interactions between defective materials and active biological proteins is crucial for evaluating the biocompatibility and biosafety of nanomaterials. This study employs molecular dynamics simulation techniques to investigate the interaction mechanisms between two types of graphene (ideal graphene and defective graphene) and two model proteins (BBA protein and λ-repressor protein). The simulation results indicate that both types of graphene exhibit superior biocompatibility with the λ-repressor protein compared to the BBA protein.
View Article and Find Full Text PDFExploring parenthood intentions and perceptions of infertility and assisted reproductive technology among 2SLGBTQIA + young adults in Ontario, Canada: a mixed methods study.
J Health Popul Nutr
January 2025
Faculty of Health Sciences, Interdisciplinary School of Health Sciences, University of Ottawa, 25 Université Priv, Ottawa, K1N 6N5, Canada.
Background: As Generation Z two-spirit, lesbian, gay, bisexual, transgender/trans, queer, intersex, asexual and others who identify as part of sexual and gender diverse communities (2SLGBTQIA +) enter adulthood, contemplation of family creation may be challenged by biological and/or social infertility. Despite some advances in societal acceptance of gender and sexual minorities, family planning and reproductive healthcare remain heteronormative. To explore reproductive decision-making and how future families are conceptualized across genders, we evaluated perceptions of Ontario, Canada non-parenting, 2SLGBTQIA + emerging adults.
View Article and Find Full Text PDFAn exploration of governance in teaching hospitals in the Netherlands focused on educational objectives.
BMC Med Educ
January 2025
SHE School of Health Professions Education, Fac. Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Background: Many countries are improving medical education in teaching hospitals through more focus on internal quality assurance, for example by creating new stakeholders like hospital-wide education committees. Adequate oversight is thought essential to ensure the quality of medical education. How teaching hospitals distribute roles and responsibilities for quality control across educational stakeholders to organize this oversight is rarely investigated.
View Article and Find Full Text PDFLigand engineering regulation toward Zn ions and Zn substrate for all-climate Zn metal batteries.
Angew Chem Int Ed Engl
January 2025
Shandong university, School of Chemistry and Chemical Engineering, No 27, Shandananlu,, 250100, Jinan, CHINA.
The regulation of artificial interphase for advanced Zn anode is an effective solution to achieve superior electrochemical performance for aqueous batteries. However, the deployment of atomically precise architectures and ligand engineering to achieve functionalization-oriented regulatory screening is lacking, which is hindered by higher requirements for synthetic chemistry and structural chemistry. Herein, we have first performed ligand engineering which selected zinc ion trapping ligands (-CH3) based on the coordination effect, and zinc substrate binding ligands (-N=N-xC6H5) based on the electrostatic interaction.
View Article and Find Full Text PDFLight-induced electron spin qubit coherences in the purple bacteria reaction center protein.
Phys Chem Chem Phys
January 2025
Chemical Sciences and Engineering Division, Argonne National Laboratory, 9700 South Cass Avenue, Lemont, Illinois 60439, USA.
Photosynthetic reaction center proteins (RCs) provide ideal model systems for studying quantum entanglement between multiple spins, a quantum mechanical phenomenon wherein the properties of the entangled particles become inherently correlated. Following light-generated sequential electron transfer, RCs generate spin-correlated radical pairs (SCRPs), also referred to as entangled spin qubit (radical) pairs (SQPs). Understanding and controlling coherence mechanisms in SCRP/SQPs is important for realizing practical uses of electron spin qubits in quantum sensing applications.
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