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Airway basal stem cell therapy for lung diseases: an emerging regenerative medicine strategy.
Stem Cell Res Ther
January 2025
Department of Pulmonary and Critical Care Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Chronic pulmonary diseases pose a prominent health threat globally owing to their intricate pathogenesis and lack of effective reversal therapies. Nowadays, lung transplantation stands out as a feasible treatment option for patients with end-stage lung disease. Unfortunately, the use of this this option is limited by donor organ shortage and severe immunological rejection reactions.
View Article and Find Full Text PDFDetection of Mycoplasma spp. from snakes from five different families.
BMC Vet Res
January 2025
LABOKLIN GmbH & Co.KG, Labor für klinische Diagnostik, Steubenstraße 4, Bad Kissingen, D-97688, Germany.
Background: Mycoplasmas are an important cause of respiratory diseases in tortoises. In snakes, evidence of mycoplasma infections has been found almost exclusively in pythons. To better understand the occurrence of these bacteria in other snake species, samples submitted for routine testing for respiratory pathogens were also tested for mycoplasma by polymerase chain reaction (PCR).
View Article and Find Full Text PDFBarriers to and facilitators of healthcare professionals in ADR reporting in a tertiary care hospital in India.
BMC Health Serv Res
January 2025
Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur , Tamil Nadu, 603203, India.
Introduction: Several adverse drug reactions (ADRs) go unreported within a healthcare setting despite the risks they cause. We therefore decided to conduct this study in order to recognize the obstacles that hinder the healthcare professionals (HCPs) in a tertiary care hospital in Kattankulathur, Tamil Nadu from reporting ADRs and what strategies ought to be implemented.
Methods: We carried out a cross-sectional study among the HCPs such as doctors, pharmacists and nurses within our institution.
Method for determining of cytotoxicity based on the release of fluorescent proteins.
BMC Mol Cell Biol
January 2025
Institute of Future Biophysics, Institutskiy per. 9, Dolgoprudny, Moscow Oblast, Moscow, Russia.
This paper describes a method for determining the cytotoxicity of chemical compounds based on the detection of fluorescent proteins-in this case, green fluorescent protein (GFP) and red fluorescent protein (RFP), which are released into the medium from dead cells. This method is similar in principle to the lactate dehydrogenase test (LDH test), but it does not require a reaction with a chromogenic substrate. This method also makes it possible to independently determine the viability of different lines when used in cocultures.
View Article and Find Full Text PDFMetadag: a web tool to generate and analyse metabolic networks.
BMC Bioinformatics
January 2025
Mathematics and Computer Science Department, University of the Balearic Islands, Ctra Valldemossa, Km 7.5, Palma, 07122, Balearic Islands, Spain.
Background: MetaDAG is a web-based tool developed to address challenges posed by big data from omics technologies, particularly in metabolic network reconstruction and analysis. The tool is capable of constructing metabolic networks for specific organisms, sets of organisms, reactions, enzymes, or KEGG Orthology (KO) identifiers. By retrieving data from the KEGG database, MetaDAG helps users visualize and analyze complex metabolic interactions efficiently.
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