Skin closures using cyanoacrylate tissue adhesives. Plastic Surgery Educational Foundation DATA Committee. Device and Technique Assessment.

Studies have been done and approval is soon possible from the FDA for an octylcyanoacrylate tissue glue for closure of lacerations of incisions. This is a newer-generation cyanoacrylate that improves on the butylcyanoacrylates currently in use in Canada and other countries but not approved by the FDA. It is a pliable, waterproof, film adhesive that can be applied to a laceration and left in place until it disintegrates in 7 to 14 days. It is safe and effective and represents an improvement over the butylcyanoacrylates that have been used for years in many countries. It is not a replacement for sutures but does offer an alternative. Some indications that seem appropriate are for closure of incisions that would be under casts; for simple lacerations in children to avoid the fear of suturing and suture removal; and for closure of incisions or lacerations where it would be a problem for a follow-up visit. This adhesive is less indicated for closure over highly mobile areas such as joints; for areas with usage and friction such as hands or feet; or for areas where exact alignment is a priority, such as the face or eyelids.