Embryology is exemplar from an epistemologic point of view, due to its close relation with philosophy as studying an immediately accessible link in the process of generation. It has evolved to its present form following the development of the microscopical techniques at the end of the 18th century, but remains close to the ancient approaches of generation. The roots of modern Embryology are still to be found in the presocratic philosophers, and the works of Aristotle represent a major step in its foundation. Embryology also had a prominent place in the reappraisal of Aristotle's work by Albertus Magnus in the middle ages, following the islamic influences. This reappraisal opened the way to the scientific movement of the Renaissance, when Leonardo da Vinci played an essential role, approaching the development of the human embryo. Embryology is therefore linked to the major influence exerted by Aristotle on occidental civilization, it has then a prominent place from a cultural point of view.
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J Orthop
August 2025
Department of Orthopaedic Surgery, Oita University Hospital, Japan.
Background: This study examines the relationship between the anterior offset of the tibial intramedullary nail (TIN) entry point and the tibial shaft axis to enhance the fit and alignment of TINs, using transparent 3D-CT in an accurate lateral view to minimize rotational artifacts.
Methods: Data were collected from 100 adult patients undergoing tibial CT scans. Measurements included the anterior offset from the tibial axis to the entry point, tibial tubercle offset, tibial plateau length, posterior slope, tibial length, isthmus diameter, and the isthmus-to-tibial length ratio.
Toxicol Res (Camb)
February 2025
Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Synthetic cathinones (SCs), a group of new psychoactive substances (NPS), are designer molecules with hallucinogenic and psychostimulatory effects. Although the structural similarities of SCs to amphetamines suggest that they may have similar toxicity profiles to those of amphetamine congeners, little is known about SCs from a toxicological point of view. In the present study, the toxicity profiles of commonly encountered SCs ( = 65), listed in the 2020 Report of the United Nations Office on Drugs and Crime (UNODC), were evaluated using in silico methods.
View Article and Find Full Text PDFJ Educ Health Promot
December 2024
Department of Nursing School, Gerash University of Medical Sciences, Gerash, Iran.
Background: One of the health problems related to tobacco that is increasing in society is the consumption of naswār. This study aimed to investigate the determinants of naswār consumption from the point of view of its consumers.
Materials And Methods: In this qualitative study, 47 men with an age range of 23- 54 years who consumed naswār from the southern cities of Fars province in Iran were selected and interviewed.
Micron
January 2025
CEMES-CNRS, 29 Rue Jeanne Marvig, Toulouse 31055, France.
Owing to its high spatial resolution and its high sensitivity to chemical element detection, transmission electron microscopy (TEM) technique enables to address high-level materials characterization of advanced technologies in the microelectronics field. TEM instruments fitted with various techniques are well-suited for assessing the local structural and chemical order of specific details. Among these techniques, 4D-STEM is suitable to estimate the strain distribution of a large field of view.
View Article and Find Full Text PDFAnal Chem
January 2025
College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
The detection of disease-related protein biomarkers plays a crucial role in the early diagnosis, treatment, and monitoring of diseases. The concentrations of protein biomarkers can vary significantly in different diseases or stages of the same disease. However, most of the existing analytical methods cannot simultaneously meet the requirements of high sensitivity and a wide dynamic range.
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