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Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife, Boston, MA, USA.
Background: Alzheimer's disease (AD) affects over 55 million people worldwide and is characterized by abnormal deposition of amyloid-β and tau in the brain causing neuronal damage and disrupting transmission within brain circuits. Episodic memory loss, executive deficits, and depression are common symptoms arising from altered function in spatially distinct brain circuits that greatly contribute to disability. Transcranial electrical stimulation (tES) can target these circuits and has shown promise to relieve specific symptoms.
View Article and Find Full Text PDFSuperconducting critical temperature elevated by intense magnetic fields.
Proc Natl Acad Sci U S A
January 2025
Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge CB3 0HE, United Kingdom.
Below a critical temperature [Formula: see text], superconductors transport electrical charge without dissipative energy losses. The application of a magnetic field [Formula: see text] generally acts to suppress [Formula: see text], up to some critical field strength at which [Formula: see text] 0 K. Here, we investigate magnetic field-induced superconductivity in high-quality specimens of the triplet superconductor candidate UTe[Formula: see text] in pulsed magnetic fields up to [Formula: see text] [Formula: see text] 70 T.
View Article and Find Full Text PDFMagnetic field-induced synergistic therapy of cancer using magnetoplasmonic nanoplatform.
Mater Today Bio
February 2025
Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, China.
Combining photothermal and chemotherapy using single nanoplatform is an emerging direction in cancer nanomedicine. Herein, a magnetic field (MF) induced combination of chemo/photothermal therapy is demonstrated using FeO@mSiO@Au core@shell@satellites nanoparticles (NPs) loaded with chemotherapeutic drug doxorubicin (DOX), both and An application of an external MF to the NPs dispersion causes magnetophoretic movement and aggregation of the NPs. While the synthesized NPs only slightly absorb light at ∼800 nm, their aggregation results in a significant near infrared (NIR) absorption associated with plasmon resonance coupling between the Au satellites in the NPs aggregates.
View Article and Find Full Text PDFMagnetic control of membrane damage in early endosomes using internalized magnetic nanoparticles.
Cell Struct Funct
December 2024
Graduate Course in Biological Sciences, Division of Science and Engineering, Graduate School of Arts and Sciences, Iwate University.
Article Synopsis
- The study explores how membrane stiffness affects cell behavior and examines the physical properties of membranes in a lab setting.
- Researchers introduced magnetic nanoparticles into breast cancer cells and used magnetic fields to see if they could damage the endosomal membrane.
- Findings show that applying a strong static magnetic field can induce membrane damage in early endosomes, particularly when using a magnetic field strength of 100 mT for five minutes, highlighting the potential for controlled damage with magnetic fields.
Spin-Polarized Scanning Tunneling Microscopy Measurements of an Anderson Impurity.
Phys Rev Lett
December 2024
II. Physikalisches Institut, Universität zu Köln, Zülpicher Straße 77, 50937 Cologne, Germany.
We report spin-polarized scanning tunneling microscopy measurements of an Anderson impurity system in MoS_{2} mirror-twin boundaries, where both the quantum-confined impurity state and the Kondo resonance resulting from the interaction with the substrate are accessible. Using a spin-polarized tip, we observe magnetic-field-induced changes in the peak heights of the Anderson impurity states as well as in the magnetic-field-split Kondo resonance. Quantitative comparison with numerical renormalization group calculations provides evidence of the notable spin polarization of the spin-resolved impurity spectral function under the influence of a magnetic field.
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