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Development of a novel molecular probe for visualizing mesothelin on the tumor via positron emission tomography.
Eur J Nucl Med Mol Imaging
January 2025
Institute of Radiation Medicine, Fudan University, Xietu Road 2094, Shanghai, 200032, China.
Objectives: Mesothelin (MSLN) is an antigen that is overexpressed in various cancers, and its interaction with tumor-associated cancer antigen 125 plays a multifaceted role in tumor metastasis. The serum MSLN expression level can be detected using enzyme-linked immunosorbent assay; however, non-invasive visualization of its expression at the tumor site is currently lacking. Therefore, the aim of this study was to develop a molecular probe for imaging MSLN expression through positron emission tomography (PET).
View Article and Find Full Text PDFSequential Growth of Quantized Peptide Brushes on Colloidal Gold.
Langmuir
January 2025
Department of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.
We synthesized rigid, macromolecular brushes with well-defined and quantized brush lengths on a gold nanoparticle substrate by using a macromolecular "grafting from" approach. The macromonomers used in these brushes were thiol- and maleimide-functionalized peptide coiled coil "bundlemers" that fold into discrete 4 nm × 2 nm (length × diameter) cylindrical nanoparticles. With each added peptide macromonomer layer, brush thickness increased by approximately the length of a single bundlemer nanoparticle.
View Article and Find Full Text PDFAn ultra-high absorptivity solar absorber with excellent thermal radiation efficiency based on a metal-dielectric stacked structure.
Phys Chem Chem Phys
January 2025
School of Physics and Optoelectronic Engineering, Yangtze University, Jingzhou, 434023, P.R. China.
Metamaterials hold great promise for application in the field of perfect absorbers due to their remarkable ability to manipulate electromagnetic waves. In this work, a full-spectrum ultra-wideband solar absorber with a multilayer metal-dielectric stacked structure is designed. Our absorber is simple and easy to manufacture, with Ti serving as the substrate, overlaid with SiN spacer layers and four pairs of Ti-SiN ring columns.
View Article and Find Full Text PDFWe propose and experimentally demonstrate what we believe to be the first mid-infrared surface plasmon resonance (SPR) fiber optic sensor using a D-shaped multimode silica optical fiber coated with a 105 nm indium tin oxide (ITO) layer. The sensor shows resonance around 2700 nm, with a refractive index sensitivity of 1065.70 nm per refractive index unit (nm/RIU) for refractive indices ranging from 1.
View Article and Find Full Text PDFA transmission-type 2-bit coding polarization conversion metasurface with radiation function is proposed in this paper. Polarization conversion is realized by two layers of grating structure and polarization conversion structure layer. Compared with conventional polarization conversion metasurface which is composed of two orthogonal grating layers and polarization conversion arrows, the two grating layers of the proposed design are parallel.
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