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Max Bergmann Center of Biomaterials Dresden, Leibniz-Institut für Polymerforschung Dresden e. V., Hohe Str. 6, 01069, Dresden, Germany.
Cell-instructive polymer hydrogels are instrumental in tissue engineering for regenerative therapies. Implementing defined and selective responsiveness to external stimuli is a persisting challenge that critically restricts their functionality. Addressing this challenge, this study introduces a versatile, modular hydrogel system composed of four-arm poly(ethylene glycol)(starPEG)-peptide and glycosaminoglycan(GAG)-maleimide conjugates.
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Ulm University: Universitat Ulm, Organic Chemistry III, Albert-Einstein-Allee 11, 89081, Ulm, GERMANY.
The efficiency of kinase inhibiting cancer therapeutics is often limited by their poor solubility in water. PEGylation is one possible strategy to improve the solubility of the drug, however, means to cleave these after reaching the target is important to make use of the therapeutic effects of the native drug. Moreover, the length of the PEG chains will have an effect on the solubility and binding.
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Sci Rep
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Department of Plant Protection, College of Agriculture, University College of Agriculture & Natural Resources, University of Tehran, Tehran, Iran.
Agaricus bisporus is globally a most extensively consumed species of edible mushrooms. Ethylene secreted by A. bisporus mycelium suppress the initiation of fructification.
View Article and Find Full Text PDFPhotoresponsive Chemistries for User-Directed Hydrogel Network Modulation to Investigate Cell-Matrix Interactions.
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Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, Colorado 80303, United States.
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Summerland Research and Development Centre, Agriculture and Agri-Food Canada, 4200 Highway 97, V0H 1Z0, Summerland, BC, Canada. Electronic address:
Plant viruses of the families Potyviridae and Secoviridae encode 3C-like proteases (3CL) that are related to picornavirus 3C proteases. This review discusses recent advances in deciphering the multifunctional activities of plant virus 3CL. These proteases regulate viral polyprotein processing and facilitate virus replication.
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