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Fieldwork on animals living in extreme conditions as a source of biomedical innovation.
Sci One Health
November 2024
CR University Grenoble Alpes, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR 5309, Grenoble, France.
Most biomedical research on animals is based on the handful of the so-called standard model organisms, i.e. laboratory mice, rats or , but the keys to some important biomedical questions may simply not be found in these.
View Article and Find Full Text PDFChemical Changes Under Heat Stress and Identification of Dendrillolactone, a New Diterpene Derivative with a Rare Rearranged Spongiane Skeleton from the Antarctic Marine Sponge .
Mar Drugs
December 2024
Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Via Campi Flegrei 34, 80078 Pozzuoli, Napoli, Italy.
The waters around the western Antarctic Peninsula are experiencing fast warming due to global change, being among the most affected regions on the planet. This polar area is home to a large and rich community of benthic marine invertebrates, such as sponges, tunicates, corals, and many other animals. Among the sponges, the bright yellow is commonly known for using secondary diterpenoids as a defensive mechanism against local potential predators.
View Article and Find Full Text PDFModulation of the modulated magnetic structure of an Ho i-MAX phase described by a magnetic (3+2)-dimensional superspace group.
Acta Crystallogr B Struct Sci Cryst Eng Mater
February 2025
Institute of Physics of the Czech Academy of Sciences, Na Slovance 1999/2, 18200 Praha 8, Czechia.
The magnetic structures of the Ho-based i-MAX phase (MoHo)GaC were studied with neutron powder diffraction at low temperature. (MoHo)GaC crystallizes in the orthorhombic space group Cmcm. The material undergoes two successive antiferromagnetic transitions at T = 10 K and T = 7.
View Article and Find Full Text PDFhemocyanin as a novel natural immunostimulant in mammals.
Front Immunol
January 2025
Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner", (INIBIOLP), Universidad Nacional de La Plata (UNLP) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), La Plata, Argentina.
Introduction: Gastropod hemocyanins are potent immunostimulants in mammals, a trait associated with their large molecular size and unusual glycosylation patterns. While the hemocyanin from the marine snail keyhole limpet (KLH), has been widely studied and successfully employed as a carrier/adjuvant in several immunological applications, as well as a non-specific immunostimulant for bladder cancer treatment, few other gastropod hemocyanins have been biochemically and immunologically characterized. In this work, we investigated the immunogenic properties of the hemocyanin from (PcH), an invasive south American freshwater snail.
View Article and Find Full Text PDFObservation of magnetic skyrmion lattice in CrMnGe by small-angle neutron scattering.
Sci Rep
January 2025
Helmholtz-Zentrum Berlin für Materialien und Energie, 13109, Berlin, Germany.
Incommensurate magnetic phases in chiral cubic crystals are an established source of topological spin textures such as skyrmion and hedgehog lattices, with potential applications in spintronics and information storage. We report a comprehensive small-angle neutron scattering (SANS) study on the B20-type chiral magnet Cr[Formula: see text]Mn[Formula: see text]Ge, exploring its magnetic phase diagram and confirming the stabilization of a skyrmion lattice under low magnetic fields. Our results reveal a helical ground state with a decreasing pitch from 40 to 35 nm upon cooling, and a skyrmion phase stable in applied magnetic fields of 10-30 mT, and over an unusually wide temperature range for chiral magnets of 6 K ([Formula: see text], [Formula: see text] K).
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