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Development of Stabilized and Aqueous Dissolvable Nanosuspension Encompassing BCS Class IV Drug via Optimization of Process and Formulation Variables.
Recent Pat Nanotechnol
January 2025
Raj Kumar Goel Institute of Technology (Pharmacy), 5-Km. Stone, Delhi-Meerut Road, Ghaziabad, Uttar Pradesh, India.
Background: Nanosuspension has emerged as an effective, lucrative, and unequalled approach for efficiently elevating the dissolution and bioavailability of aqueous soluble drugs. Diverse challenges persist within this domain, demanding further comprehensive investigation and exploration.
Objective: This study aims to design, develop, optimise formulation and process variables, and characterise the stabilised aqueous dissolvable nanosuspension using chlorthalidone as a BCS class- IV drug.
Ultrasonic assisted enzymolysis based modification of native banana starch - A comprehensive analyses of the structural, morphological, rheological and textural properties.
Int J Biol Macromol
January 2025
ICAR-National Institute of Abiotic Stress Management, Malegaon, Baramati, M.S., India.
Native banana starch (NS) has few limitations, such as poor solubility, low resistance to shear, temperature, and inconsistent retrogradation. This study investigates the effects of mono (α-amylase, pullulunase) and sequential enzymatic modifications of NS along with the application of ultrasound to enhance its functional attributes. Starch modified with α-amylase alone and along with ultrasound resulted the lowest amylose (20.
View Article and Find Full Text PDFThe accurate determination of Perfluorooctane sulfonic acid (PFOS) removal efficiency by integrated-sonochemical system.
Ultrason Sonochem
January 2025
Université Paris Cité, Institut de Physique du Globe de Paris, CNRS, F-75005 Paris, France. Electronic address:
Perfluorooctanesulfonic acid (PFOS) is one of the most investigated Per- and polyfluoroalkyl substances (PFAS) for being the strongest compound to eliminate and having adverse health concerns. In this work, we have conducted the sonochemical treatment of PFOS simulated water under high (500 kHz) and low (22 kHz) frequencies while monitoring the operational parameters via an integrated sonochemical system. The integrated advanced sonochemical system includes software to monitor treatment power, solution temperature and frequency while allowing distinctive control of the reaction conditions.
View Article and Find Full Text PDFAn Investigation into High-Accuracy and Energy-Efficient Novel Capacitive MEMS for Tire Pressure Sensor Application.
Sensors (Basel)
December 2024
School of Instrument and Electronics, North University of China, Taiyuan 030051, China.
Tire pressure monitoring systems (TPMSs) are essential for maintaining driving safety by continuously monitoring critical tire parameters, such as pressure and temperature, in real time during vehicle operation. Among these parameters, tire pressure is the most significant, necessitating the use of highly precise, cost-effective, and energy-efficient sensing technologies. With the rapid advancements in micro-electro-mechanical system (MEMS) technology, modern automotive sensing and monitoring systems increasingly rely on MEMS sensors due to their compact size, low cost, and low power consumption.
View Article and Find Full Text PDFDiluting Ionic Liquids with Small Functional Molecules of Polypropylene Carbonate to Boost the Photovoltaic Performance of Perovskite Solar Cells.
Molecules
December 2024
Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China.
It is necessary to overcome the relatively low conductivity of ionic liquids (ILs) caused by steric hindrance effects to improve their ability to passivate defects and inhibit ion migration to boost the photovoltaic performance of perovskite solar cells (PSCs). Herein, we designed and prepared a kind of low-concentration 1-butyl-3-methylimidazolium tetrafluoroborate (BMIMBF) diluted with propylene carbonate (PC) via an ultrasonic technique (PC/IL). The decrease in the decomposition temperature related to the IL part and the increase in the sublimation temperature related to the PC part facilitated the use of PC/IL to effectively delay the crystallization process and passivate the defects in multiple ways to obtain high-quality perovskite films.
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