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http://dx.doi.org/10.1097/00005373-199901000-00031 | DOI Listing |
Sci Rep
September 2023
Department of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Detection and differentiation of brown fat in humans poses several challenges, as this tissue is sparse and often mixed with white adipose tissue. Non-invasive detection of beige fat represents an even greater challenge as this tissue is structurally and functionally more like white fat than brown fat. Here we used positron emission tomography with F-fluorodeoxyglucose, computed tomography, xenon-enhanced computed tomography, and dynamic contrast-enhanced ultrasound, to non-invasively detect functional and structural changes associated with the browning process of inguinal white fat, induced in mice by chronic stimulation with the β-adrenergic receptor agonist CL-316243.
View Article and Find Full Text PDFStroke Res Treat
July 2011
Department of Neurology, The Hospital of the University of PA, 3400 Spruce Street, Philadelphia, PA, 19104, USA.
Background. Cervicocephalic arterial dissection (CCAD) is rare in the postpartum period. To our knowledge this is the first reported case of postpartum angiopathy (PPA) presenting with ischemic stroke due to intracranial arterial dissection.
View Article and Find Full Text PDFNeurosurg Focus
April 2009
Department of Neurosurgery, Stanford Stroke Center, Stanford, California, USA.
Moyamoya disease is characterized by a chronic stenoocclusive vasculopathy affecting the terminal internal carotid arteries. The clinical presentation and outcome of moyamoya disease remain varied based on angiographic studies alone, and much work has been done to study cerebral hemodynamics in this group of patients. The ability to measure cerebral blood flow (CBF) accurately continues to improve with time, and with it a better understanding of the pathophysiological mechanisms in patients with moyamoya disease.
View Article and Find Full Text PDFJ Neurosurg
January 2008
Baylor College of Medicine, Houston, Texas 77030, USA.
Objectives: Increasing PaO2 can increase brain tissue PO2 (PbtO2). Nevertheless, the small increase in arterial O2 content induced by hyperoxia does not increase O2 delivery much, especially when cerebral blood flow (CBF) is low, and the effectiveness of hyperoxia as a therapeutic intervention remains controversial. The purpose of this study was to examine the role of regional (r)CBF at the site of the PO2 probe in determining the response of PbtO2 to induced hyperoxia.
View Article and Find Full Text PDFNeurocrit Care
January 2006
Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA, and Department of Neurosurgery, University Hospital, Charles' University, Hradec Kralove, Czech Republic.
Background: It is controversial whether a low cerebral blood flow (CBF) simply reflects the severity of injury or whether ischemia contributes to the brain's injury. It is also not clear whether posttraumatic cerebral hypoperfusion results from intracranial hypertension or from pathologic changes of the cerebral vasculature. The answers to these questions have important implications for whether and how to treat a low CBF.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!