Study Objective: To evaluate the efficacy and safety of combined oral and vaginal administration of antibiotics.
Design: Treatment and follow-up examination of 54 cases of severe vulvovaginitis.
Setting: Division of Pediatric and Adolescent' Gynecology, Second Department of Obstetrics and Gynecology, University of Athens, Greece.
Participants: Girls aged 1-10 years seen at the clinic of the above-listed institution.
Interventions: Vaginal application of antibiotics.
Main Outcome Measures: Vaginal culture and vaginoscopy.
Results: Treatment achieved microbial eradication in 51 of 54 patients (94%). In most patients, relief of symptoms was achieved after 2-3 days. No adverse effects were reported.
Conclusions: Treatment was highly effective and simple to administer, and no complications were observed. A further advantage of this approach is the shorter duration of treatment.
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