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Discordance, accuracy and reproducibility study of pathologists' diagnosis of melanoma and melanocytic tumors.
Nat Commun
January 2025
Digital Biomarkers for Oncology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Accurate melanoma diagnosis is crucial for patient outcomes and reliability of AI diagnostic tools. We assess interrater variability among eight expert pathologists reviewing histopathological images and clinical metadata of 792 melanoma-suspicious lesions prospectively collected at eight German hospitals. Moreover, we provide access to the largest panel-validated dataset featuring dermoscopic and histopathological images with metadata.
View Article and Find Full Text PDFProblems when diagnosing cutaneous leishmaniasis: a retrospective study analyzing clinical, histopathological and immunohistochemical features.
J Dtsch Dermatol Ges
December 2024
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
Background: Cutaneous leishmaniasis (CL) incidence in Switzerland is rising due to factors like migration and globalization. The aim of this work was to investigate CL frequency in Switzerland and identify clinical and histopathological difficulties in diagnosing CL in a non-endemic country.
Patients And Methods: This retrospective study evaluated the clinical and histopathological characteristics of all CL cases from two dermatopathology laboratories between 2000 and 2022.
Diagnostic challenges in cutaneous leishmaniasis due to atypical : pathologists' insights from re-emergence zones.
Front Med (Lausanne)
September 2024
Division of Malaria Immunology, Department of Microbiology and Immunology, Institute of Medical Science (IMSUT), The University of Tokyo, Tokyo, Japan.
Article Synopsis
- - The study focuses on the rising incidence of cutaneous leishmaniasis (CL) in Türkiye due to migration and environmental changes, noting that it’s appearing in places where it was previously unknown, leading to misdiagnosis by physicians unfamiliar with the disease.
- - Researchers performed a retrospective analysis of 12 CL cases diagnosed from 2013 to 2022, looking at clinical presentation, pre-diagnosis, histopathological findings, and DNA analysis to confirm species involved.
- - Findings show that only 58.3% of cases considered CL in their pre-diagnosis; others were misdiagnosed, often as skin tumors, with patients presenting non-healing skin lesions that required further evaluation.
Tuberculous Ulcerative Skin Lesion of the Penis: A Case Report.
Infect Drug Resist
July 2024
Department of Dermatology and Venereology, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, People's Republic of China.
Genitourinary tuberculosis (GUTB), especially penile tuberculosis (PTB), is a disease often overlooked by urological specialists, especially in Europe, where the pathology is less frequent. In this report, we described a case of penile tuberculosis (PTB) characterized by ulcers on the penis. After the patient was administered three months of anti-tuberculosis treatment (isoniazid 0.
View Article and Find Full Text PDFIncreasing trend in confirmed scabies cases in the only public dermatological institute of scientific research and care in Italy.
Eur J Dermatol
December 2023
STI/HIV Unit, San Gallicano Dermatological Institute IRCCS, Via Elio Chianesi 53, 00144, Rome, Italy.
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