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Precision in Liver Diagnosis: Varied Accuracy Across Subgroups and the Need for Variable Thresholds in Diagnosis of MASLD.
Liver Int
February 2025
Department of Epidemiology and Data Science, Amsterdam University Medical Centres, Amsterdam, The Netherlands.
Background And Aims: The performance of non-invasive liver tests (NITs) is known to vary across settings and subgroups. We systematically evaluated whether the performance of three NITs in detecting advanced fibrosis in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) varies with age, sex, body mass index (BMI), type 2 diabetes mellitus (T2DM) status or liver enzymes.
Methods: Data from 586 adult LITMUS Metacohort participants with histologically characterised MASLD were included.
Association of liver fibrosis with aneurysm size and mortality risk in patients undergoing open abdominal aortic aneurysm repair.
Sci Rep
January 2025
Thoracic and Vascular Surgery Research Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Abdominal Aortic Aneurysm (AAA) poses a significant health risk due to its silent nature and high mortality upon rupture. The Fib-4 index, initially designed for liver fibrosis assessment, presents potential beyond its scope. This study aims to investigate the association of FIB-4 with aneurysm size and mortality risk, exploring its utility as a risk predictor for enhanced clinical management.
View Article and Find Full Text PDFDose verification of 2 targets simultaneously for single-isocenter stereotactic radiation therapy and radiosurgery plans.
Med Dosim
January 2025
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.
Most of conventional 2-dimensional (2D) methods verify dose of multiple targets separately one-by-one for Single-isocenter Multiple-target (SIMT) brain plans, which are inefficient and sub-optimal. This study presented a practical method to verify the dose of 2 targets simultaneously for improved efficiency and accuracy. Fifteen Stereotactic Radiation Therapy (SRT) and sixteen Stereotactic Radiosurgery (SRS) plans were used for this study.
View Article and Find Full Text PDFSystemic Immune-inflammation Index Is Associated with Symptomatic Cerebral Hyperperfusion after Revascularization Surgery in Moyamoya Disease.
Neurol Med Chir (Tokyo)
January 2025
Department of Neurosurgery, Hokkaido University Graduate School of Medicine.
Revascularization surgery for moyamoya disease poses risks of complications, requiring appropriate management. Although precise prediction is difficult, the systemic immune-inflammation index is a calculable marker that reflects systemic inflammatory conditions. We aimed to investigate the association between postoperative complications and the systemic immune-inflammation index.
View Article and Find Full Text PDFCausal Inference for Hypertension Prediction With Wearable E lectrocardiogram and P hotoplethysmogram Signals: Feasibility Study.
JMIR Cardio
January 2025
School of Life Science and Technology, University of Electronic Science and Technology of China, Research Building C348A, 3rd Fl, Chengdu, 611731, China, 86 18030493605.
Background: Hypertension is a leading cause of cardiovascular disease and premature death worldwide, and it puts a heavy burden on the healthcare system. Therefore, it is very important to detect and evaluate hypertension and related cardiovascular events to enable early prevention, detection, and management. Hypertension can be detected in a timely manner with cardiac signals, such as through an electrocardiogram (ECG) and photoplethysmogram (PPG) , which can be observed via wearable sensors.
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