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Deep-Reticular Pseudodrusen-Net: A 3-Dimensional Deep Network for Detection of Reticular Pseudodrusen on OCT Scans.
Ophthalmol Sci
November 2024
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland.
Objective: To propose Deep-RPD-Net, a 3-dimensional deep learning network with semisupervised learning (SSL) for the detection of reticular pseudodrusen (RPD) on spectral-domain OCT scans, explain its decision-making, and compare it with baseline methods.
Design: Deep learning model development.
Participants: Three hundred fifteen participants from the Age-Related Eye Disease Study 2 Ancillary OCT Study (AREDS2) and 161 participants from the Dark Adaptation in Age-related Macular Degeneration Study (DAAMD).
Octa-Cationic Porphyrin-Functionalized Biocompatible Nanocomposite: A Promising Candidate for Enhanced Combinatorial Photodynamic and Photothermal Tumor Therapy.
J Med Chem
January 2025
Department of Chemistry, Tianjin University, Tianjin 300072, China.
The integration of photodynamic therapy (PDT) and photothermal therapy (PTT) offers a promising strategy for enhancing phototherapy efficiency. Herein, we present a dual-functional, biocompatible nanocomposite system for combination PDT/PTT therapy. The system utilizes a highly biocompatible nanoparticle assembled by an amphiphilic short peptide with the assistance of Zn as a carrier.
View Article and Find Full Text PDFA randomized control trial to compare Quiet Eye training efficacy to traditional technical training with undergraduate student nurses' peripheral intravenous cannulation performance: a protocol.
Br J Nurs
January 2025
Department of Psychology, Faculty of Arts, University of Calgary, Alberta, Canada; Community Health Sciences, Faculty of Medicine, University of Calgary, Alberta, Canada; Ward of the 21st Century, Cumming School of Medicine, University of Calgary, Alberta, Canada.
Introduction: Peripheral intravenous cannulation (PIVC) is a common and complex procedure with low first-attempt success rates, causing patient suffering and increased healthcare costs. Quiet Eye (QE) training, a gaze-focused approach, has shown promise in improving procedural PIVC skills. We will examine the effectiveness of traditional technical training (TT) and QE training (QET) on student nurse PIVC performance.
View Article and Find Full Text PDFIntracellular dark endothelial spots detected using specular microscopy are associated with graft failure after Descemet's membrane endothelial keratoplasty.
Graefes Arch Clin Exp Ophthalmol
January 2025
Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.
Purpose: To investigate the correlation between intracellular dark endothelial spots (IDESs) detected by specular microscopy and the incidence of graft failure after Descemet's membrane endothelial keratoplasty (DMEK).
Methods: We reviewed 100 consecutive DMEK patients performed by a single surgeon at two centres between January 2015 and July 2022. Central corneal thickness was evaluated using anterior segment optical coherence tomography (SS-1000; Tomey, Aichi, Japan), and endothelial cell density was measured using specular microscopy.
Hidden Urban Biodiversity: A New Species of the Genus Mittleman, 1950 (Squamata: Scincidae) from Chengdu, Sichuan Province, Southwest China.
Animals (Basel)
January 2025
CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan Province, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610213, China.
The genus Mittleman, 1950, belonging to the family Scincidae, exhibits considerable morphological convergence, complicating species delimitation and resulting in underestimated diversity. Currently, 41 species are formally recognized in this genus, although this figure likely underestimates its true richness. In this study, a new species of the genus , , is described from urban and suburban areas of Chengdu, Sichuan Province, Southwest China.
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