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Infarct core segmentation using U-Net in CT perfusion imaging: a feasibility study.
Acta Radiol
January 2025
Department of Medical Imaging, Dalin Tzu-Chi Hospital, Chiayi, Taiwan.
Background: The wide variability in thresholds on computed tomography (CT) perfusion parametric maps has led to controversy in the stroke imaging community about the most accurate measurement of core infarction.
Purpose: To investigate the feasibility of using U-Net to perform infarct core segmentation in CT perfusion imaging.
Material And Methods: CT perfusion parametric maps were the input of U-Net, while the ground truth segmentation was determined based on diffusion-weighted imaging (DWI).
Developments and clinical experiences in collagenase chemonucleolysis for lumbar disc herniation: a narrative review.
Front Med (Lausanne)
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Department of Orthopedic, Dianjiang People's Hospital of Chongqing, Chongqing, China.
Lumbar disc herniation (LDH) affects millions globally, with annual healthcare costs exceeding $100 billion in the United States alone, driving increasing interest in minimally invasive radiological interventions as treatment alternatives. This narrative review examines developments in collagenase chemonucleolysis for LDH, integrating a literature analysis with clinical experience. Key advancements include the transition from single-agent to combination therapies, exploration of diverse injection routes, and the progression from C-arm fluoroscopy to multi-slice CT guidance.
View Article and Find Full Text PDFTransforming healthcare: Saudi Arabia's vision 2030 healthcare model.
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School of Medical and Life Sciences, Sunway University, Sunway City, Malaysia.
Vision 2030 represents Saudi Arabia's strategic socio-economic plan aimed at promoting economic diversification and enhancing living standards. Launched in April 2016, this vision describes an innovative healthcare plan to improve services and outcomes. The merits and drawbacks of public hospitals' 'Model of Care' are examined in this study.
View Article and Find Full Text PDFDisruption of biological membranes by hydrophobic molecules: a way to inhibit bacterial growth.
Front Microbiol
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Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional Unidad Monterrey, Apodaca, Nuevo León, Mexico.
With antibiotic resistance increasing in the global population every year, efforts to discover new strategies against microbial diseases are urgently needed. One of the new therapeutic targets is the bacterial cell membrane since, in the event of a drastic alteration, it can cause cell death. We propose the utilization of hydrophobic molecules, namely, propofol (PFL) and cannabidiol (CBD), dissolved in nanodroplets of oil, to effectively strike the membrane of two well-known pathogens: and .
View Article and Find Full Text PDFU.S. State-Level Containment Policies Not Associated with Food Insecurity Changes During the Early COVID-19 Pandemic: A Multi-level Analysis.
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Johns Hopkins Center for a Livable Future, Johns Hopkins University, Baltimore, MD, 21205, USA.
Objective: To investigate the relationship between United States (US) containment measures during the COVID-19 pandemic and household food insecurity.
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