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Article Synopsis
  • Febrile illnesses that persist despite initial treatment are a common issue in low-resource subtropical settings, often caused by infectious diseases that are neglected and have limited diagnostic options.
  • A systematic review was conducted across 196 articles from various countries in Africa, Asia, and Central/South America, focusing on "prolonged fevers" in adults and children while excluding well-known diseases like malaria and TB.
  • Among the neglected diseases identified, rickettsioses and relapsing fever borreliosis were the most common causes reported, particularly in Eastern Africa, along with other diseases such as brucellosis and leishmaniasis.
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() infections typically present with fever and gastrointestinal symptoms. This case report on enteritis documents atypical clinical, radiological, and endoscopic findings raising diagnostic challenges. A 31-year-old male in the Kingdom of Saudi Arabia (KSA) presented with severe abdominal pain, vomiting, bloody diarrhea, and no fever.

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A systematic review of neglected tropical diseases (NTDs) in Myanmar.

PLoS Negl Trop Dis

November 2023

Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.

Background: Neglected tropical diseases (NTDs) affect most impoverished communities in developing countries, like Myanmar in Southeast Asia. NTDs have been understudied and underreported in Myanmar.

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Prevalence of Blastocystis and Dientamoeba fragilis in diarrheal patients in Corum, Türkiye.

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Division of Medical Parasitology, Department of Medical Microbiology, Faculty of Medicine, Gazi University, Ankara, Turkey.

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  • The study identified common subtypes of Blastocystis, with ST3 being the most prevalent, particularly in individuals aged 40-59 years, while D. fragilis was found in 8.4% of participants without significant differences between the two groups.
  • Co-infection rates were high at 58.3%, more frequent in healthy individuals, and other pathogens like Entamoeba histolytica and Giardia
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Anti-infective treatment of gastro-intestinal tract infections in children.

Infect Dis Now

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Gastroenteritis is most often viral in origin and Rotavirus and Norovirus most frequently implicated in young children. Stool-based multiplex Polymerase Chain Reaction (PCR) can detect bacteria, viruses or parasites that may or may not be responsible for gastroenteritis (colonization). While the etiological profile of these digestive infections has greatly benefited from PCR, in the absence of underlying pathologies the presence of potential pathogens does not justify anti-infectious treatment.

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