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Lichen planus of the esophagus: a case report.
Front Med (Lausanne)
December 2023
Department of Gastroenterology, Hospital Universitari Doctor Josep Trueta de Girona, Girona, Spain.
Esophageal lichen planus (ELP) is an inflammatory disorder that affects the skin, cutaneous appendages and mucous membranes. The esophageal involvement is rare. We present the case of a 70-year-old woman with years of dysphagia and a history of erosive lichen planus involving the vulva, vagina, gingiva, and skin, who was eventually diagnosed with esophageal lichen planus.
View Article and Find Full Text PDFLigneous periodontitis exacerbated by Behçet's disease in a patient with plasminogen deficiency and a stop-gained variant PLG c.1468C > T: a case report.
BMC Oral Health
November 2023
Department of Pathophysiology-Periodontal Science, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-Cho, Kita-Ku, Okayama, 700-8525, Japan.
Background: Plasminogen serves as the precursor to plasmin, an essential element in the fibrinolytic process, and is synthesized primarily in the liver. Plasminogen activation occurs through the action of plasminogen activator, converting it into plasmin. This conversion greatly enhances the fibrinolytic system within tissues and blood vessels, facilitating the dissolution of fibrin clots.
View Article and Find Full Text PDFVulvar-vaginal-gingival-otic syndrome.
Exp Dermatol
January 2024
Department of Dermatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
In order to retrospectively analyse the multi-site involvement pattern of erosive lichen planus patients, we retrospectively reported the clinical and medical data of three patients with erosive lichen planus which involving their vulva, vagina, gingiva, and ear canal. We confirmed the existence of otic lichen planus, and found that it is more common in patients with vulvovaginal-gingival syndrome of erosive lichen planus. Therefore, we propose 'vulvovaginal-gingival-otic syndrome' to further describe this rare compound pattern of lichen planus.
View Article and Find Full Text PDFVerruciform Xanthoma: Clinical and Morphologic Spectrum Across Oral, Genital, and Cutaneous Sites.
Head Neck Pathol
September 2023
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Background: Verruciform xanthoma (VX) is an uncommon, benign epithelial lesion of the oral mucosa. While this entity can also present extraorally, including on the skin and in anogenital areas, the variation in its histologic features in extraoral sites is not yet well defined. Differences in the demographics and morphologic features of oral versus extraoral VX were assessed to help facilitate the accurate diagnosis and management of this lesion.
View Article and Find Full Text PDFP048 Metastatic Crohn's Disease Debuting with Severe Oral Manifestation and Vulvar Involvement - A Diagnostic Challenge.
Am J Gastroenterol
December 2021
Gastroenterología y Endoscopia Digestiva, Hospital Internacional de Colombia, Bucaramanga, Colombia. Grupo de Inmunología Celular y Molecular-InmuBo, Universidad del Bosque, Bogota, Colombia.
Article Synopsis
- - The text discusses a rare case of metastatic Crohn's disease (MCD) presenting with severe oral and vulvar lesions, leading to the extraction of numerous teeth and significant discomfort, without gastrointestinal symptoms.
- - The patient, who has a family history of autoimmune conditions, exhibited symptoms like severe gingivitis, ulcers, and lip edema, prompting initial considerations for Behçet's disease but ultimately diagnosed with MCD after negative tests for other conditions.
- - Management included topical steroids for skin lesions and dental implants for oral issues, along with the introduction of anti-TNF treatment Adalimumab, which led to the development of paradoxical psoriasis as a side effect.
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