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Background: Acute infectious purpura fulminans (AIPF) is a rare but potentially fatal postoperative complication characterised by rapidly progressing disseminated intravascular coagulation (DIC), widespread purpura, and multi-organ dysfunction. Despite its severe and critical outcomes, the literature on this condition in the postoperative context is limited.

Objectives: This study aimed to analyse and evaluate the incidence, clinical presentation, laboratory findings, management strategies, and outcomes of postoperative AIPF in patients who underwent various surgical procedures.

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Article Synopsis
  • The paper discusses the first use of split-thickness skin autografts soaked in platelet-rich plasma (PRP) and cryoprecipitate for treating second and third-degree burns in four patients of different ages.
  • These patients had burns covering 10% to 35% of their total body surface area, and the treatment involved applying the autografts along with dressings soaked in the same mixture, leading to successful healing.
  • The findings suggest that this method enhances skin healing processes, making it a promising approach for improving outcomes in burn treatment.
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Uncommon defibrinogenation and coagulopathy caused by Trimeresurus stejnegeri stejnegeri envenomation in a patient with swelling above the ankle.

Toxicon

October 2022

Division of Clinical Toxicology, Department of Emergency Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; College of Medicine, National Chung Hsing University, Taichung, Taiwan. Electronic address:

In Taiwan, Trimeresurus stejnegeri stejnegeri (Stejneger's Bamboo pitviper) is responsible for more than half of all venomous snakebites annually. This species often causes local envenoming characterized by tissue swelling and pain, occasional local ecchymosis, bullae and blister formation, and lymphangitis and lymphadenitis. The pathophysiology and treatment of potentially life-threatening coagulopathy and defibrinogenation induced by T.

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[Treatment of chronic refractory wound with autologous platelet-rich plasma in a hemophilia A patient after knee joint surgery].

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi

April 2022

Department of Burns and Plastic Surgery, Maoming People's Hospital, Maoming 525099, China.

On December 22, 2017, a 35-year-old male hemophilia A patient with a secondary chronic refractory wound after left knee joint surgery was transferred from the Department of Hematology of Maoming People's Hospital to the Department of Burns and Plastic Surgery in the same hospital. The physical examination revealed that the patient's left knee joint was swollen, with a full-thickness skin defect wound of 4 cm×4 cm on the lateral side of the joint and a large number of dark red blood clots at the bottom of the wound. The wound bleeding was controlled by intravenous infusion of plasma, cryoprecipitate, and human coagulation factor Ⅷ.

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Cocktail Protocol for Preparation of Platelet-Rich Fibrin Glue for Autologous Use.

Malays J Med Sci

February 2021

Department of Immunohematology and Blood Transfusion, Kasturba Medical College of Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Background: Biomaterials containing platelets have been used to promote healing of ulcers and burns, as well as in implantology and maxillofacial and plastic surgery to achieve wound healing and tissue repair. Commercial devices to prepare autologous biomaterials involve diverse preparation methods that can have high production costs and low yields. Hence, we designed a protocol for preparation of large amounts of autologous platelet-rich fibrin (PRF) glue using conventional processing techniques for blood components.

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