One, two-disubstituted carbocyclic nucleoside analogues bearing a 2-amino-6-substituted (chloro, hydroxy or amino) purine or 8-azapurine base were prepared by constructing the base about (+/-)-2-aminocyclopentane methanol, and their activities against a selection of viruses and tumor cells were determined in vitro.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0960-894x(98)00216-9 | DOI Listing |
Publication Analysis
Top Keywords
purine 8-azapurine
8
synthesis biological
4
biological evaluation
4
evaluation 12-disubstituted
4
12-disubstituted carbonucleosides
4
carbonucleosides 2-amino-6-substituted
4
2-amino-6-substituted purine
4
8-azapurine two-disubstituted
4
two-disubstituted carbocyclic
4
carbocyclic nucleoside
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!