Daughters comprise 29% of all caregivers of the dependent elderly and make decisions about parent care in a context of ambiguous and changing role expectations. This qualitative study explored the decision process of ten caregiving daughters. The women responded to parent dependency with an impulse to care and pursued a balancing point of care in the face of limiting decision conditions. Each daughter constructed a sense of "enough": an equation of her multiply-determined impulse to care and her personal threshold of support. These constructions help explain the variability of levels, lengths, and forms of parent care.
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http://dx.doi.org/10.1300/J074v10n02_05 | DOI Listing |
J Ren Care
March 2025
Department of Renal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Background: Nursing sensitive indicators are a way of measuring aspects of patient care that are most affected by the actions of the nurse. Despite the existence of nursing sensitive indicators, these are largely not suitable to measure peritoneal dialysis nursing practice.
Objective: This project aimed to co-develop a set of peritoneal dialysis nursing-sensitive indicators.
Life Metab
February 2025
Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore.
Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme in the pentose phosphate pathway (PPP) in glycolysis. Glucose metabolism is closely implicated in the regulation of mitophagy, a selective form of autophagy for the degradation of damaged mitochondria. The PPP and its key enzymes such as G6PD possess important metabolic functions, including biosynthesis and maintenance of intracellular redox balance, while their implication in mitophagy is largely unknown.
View Article and Find Full Text PDFToxicol Mech Methods
January 2025
Department of Pharmacology, SVKM's NMIMS School of Pharmacy and Technology Management, Babulde, Shirpur, 425405 Maharashtra, India.
Adverse drug reactions (ADR) remain a challenge in modern healthcare, particularly given the increasing complexity of therapeutics. WHO's definition of an adverse drug reaction as a response to a drug that is noxious and unintended and occurs at doses normally used in man for the prophylaxis, diagnosis or therapy of disease, or for modification of physiological function. This definition underscores the importance of monitoring and mitigating unintended drug effects, particularly for widely used medications like valproic acid (VPA).
View Article and Find Full Text PDFBMC Nurs
January 2025
School of Nursing, Hangzhou Normal University, No. 2318 Yuhangtang Road, Hangzhou, Zhejiang Province, 31121, China.
Background: Nurses' competency in pain management is essential for effectively alleviating patients' acute pain, controlling chronic pain, and promoting patient recovery. However, reliable tools for evaluating these competencies across different clinical specialties and healthcare settings are lacking. This study aimed to develop and validate a Pain Management Competency Scale for Nurses (PMCSN) and to assess the pain management competencies of nurses in China through a nationwide survey.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523-1872, United States.
Enthalpy is often the focal point when designing monomers for polymer circularity, but much less is explored on how entropy can be exploited to create polymers with synergistic circularity and properties. Here, we design a series of spiro-lactones (SLs) with closed-chain cycloalk(en)yl substituents at the α,α-position of δ-valerolactone (δVL), which, when combined with the parent δVL and -α,α-dialkyl-substituted δVL with open-chain alkyl groups, provide a desired platform for exploring the circular polymer design by focusing on the entropy change of polymerization. These SLs exhibit finely balanced (de)polymerizability that is regulated chiefly by entropy differentiation, allowing both the facile synthesis of polyester PSLs ( up to 1000 kg mol) in a living fashion and selective depolymerization of the PSLs to completely recover monomers under mild conditions (using a recyclable catalyst at 100 °C).
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