Purpose: The efficacy of the reduction time (tau) after castration as a prognostic factor was examined by comparing to Gleason score.

Materials And Methods: The change of prostatic volume after castration was observed from the castration to 3 months after in 24 cases of prostatic cancer. Prostatic volume was examined by transrectal ultrasonography of the prostate. Survival curves was calculated by Kaplan-Meier method. Differences among survival curves were analyzed using Cox-Mantel test.

Results: tau had a close relationship to the prognosis of each case (Wilcoxon test: p < 0.05, Cox-Mantel test: p < 0.05). Gleason score had a weak relationship to prognosis (Wilcoxon test: N. S., Cox-Mantel test: p < 0.05).

Conclusions: tau was efficient as prognostic factor compared to Gleason score.

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http://dx.doi.org/10.5980/jpnjurol1989.89.871DOI Listing

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