The CoaguChek system is a new system for simple self-testing of prothrombin time from capillary blood. The instrument works with a measuring principle which is completely new in coagulation: the motion of magnetic micro-particles in an oscillating magnetic field is stopped by the fibrin clot and is detected by a photodetector. The existing data show the analytical and clinical reliability of the system. Determinations for within series imprecision yielded a mean CV of 4.9%. The system is comparable to the comparison method Hepato Quick (y = 1.07 x -0.9% Quick; r = 0.89). Patient self-testing increases the relative time within therapeutic range from 54% to 84%.
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