The comparative analysis of content prostaglandins E2, F2 alpha and cAMP, cGMP in the compositions of the high-molecular aminoacyl-tRNA synthetase complexes and endoplasmic reticulum vesicules from the rat liver has been carried out. The influence of lethal and sublethal X-ray doses on the levels of cyclic nucleotides and prostaglandins has been studied. Cyclic nucleotides and prostaglandins proved to be rapid and high sensitive transmitters of ionizing radiation influence on the eukaryotic translation apparatus.

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