The level of IgG1 in blood in cows of different ages before calving is decreased. At antigens stimulation the content of the IgG1 increases in about twice at the expense of specific antibodies connected with antigens which are and transferred into colostrum. The maximum antibodies (IgG1) level is marked in colostrum of mature cows (2-7 lactations) and it reaches of 82.8 mg/ml and the minimum level in the first-born calves-51.6 mg/ml. Correspondingly the calves from the first-born cows assimilated 28-36% less immunoglobulins than the calves of the same ages from the cows of older ages.
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