[Ca2+/H+ exchange in the lymphocyte plasma membrane].

We studied delta pH-induced Ca(2+)-transport through the lymphocytes plasma membrane. The simultaneous and reversal H(+)-counter transport of Ca2+ was shown in the presence of known Ca(2+)- and H(+)-transporting pathways through the plasma membrane. Ca2+/H+ exchange through the plasma membrane was shown experimentally on the plasma membrane of lymphocytes, obtained from fresh rats' blood under the conditions of inhibition for known Ca2+ and H+ conductive pathways. At least one of the transporting cations' concentration gradient through the outer plasma membrane was only the moving force for the such exchange. Cytoplasmic H(+)-buffering capacity changing and associated plasma membrane's delta pH changing are discussed to imply on redistribution of Ca2+ through the plasma membrane. We suggest the presence of Ca2+/H+ antiporter in the lymphocytes' plasma membrane.