The data of detailed biochemical analysis of the schizophrenic patients with febrile psychoses suggest the differences in the blood enzymatic spectrum between different types of this disease (spontaneous febrile schizophrenia, malignant neuroleptic syndrome, generalised allergic reaction). The activity of the plasma enzymes is correlated with febrile syndrome and clinical manifestation of the disease, its highest level is observed in patients with malignant neuroleptic syndrome. The role of the cytolysis in clinical manifestation different types of psychoses is discussed.

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