Training and recovery of instrumental equilibrium reflexes are impossible after total neurotoxical destruction of the inferior olive in rats. Motor deficits and compensatory rehabilitation processes in rats following 3-acethylpyridine treatment and high transection of the dorso-lateral funiculus of the spinal cord are closely correlated with the degree of the inferior olive destruction. The data obtained revealed an improvement in the motor disturbance and a stabilising of the instrumental reflexes in the rats with subtotal lesion of the inferior olive.
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Volumetric alterations in auditory and visual subcortical nuclei following perinatal deafness in felines.
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Integrated Program in Neuroscience, McGill University, Montreal, Quebec, Canada; Department of Physiology, McGill University, Montreal, Quebec, Canada. Electronic address:
In response to sensory deprivation, the brain adapts to efficiently navigate a modified perceptual environment through a process referred to as compensatory crossmodal plasticity, allowing the remaining senses to repurpose deprived regions and networks. A mechanism that has been proposed to contribute to this plasticity involves adaptations within subcortical nuclei that trigger cascading effects throughout the brain. The current study uses 7T MRI to investigate the effect of perinatal deafness on the volumes of subcortical structures in felines, focusing on key sensory nuclei within the brainstem and thalamus.
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