AI Article Synopsis
- The study aimed to see if respiratory system compliance and lung resistance could predict chronic lung disease (CLD) in preterm infants.
- Researchers analyzed 48 preterm infants under 1500 g who required ventilation, measuring pulmonary mechanics at specific days of life.
- Results showed that infants who didn't develop CLD had higher dynamic compliance values from day 5, and lung resistance values differed significantly between groups starting from day 7, suggesting Crsdyn is a useful predictor for CLD.
Article Abstract
Background: The objective of this study was to determine if the value of respiratory system compliance and lung resistance could be a good predictor of chronic lung disease (CLD) in an early stage of this disease.
Methods: The study was carried out on 48 preterms infant (BW < 1500 g) who were ventilated for respiratory distress, calculating pulmonary mechanics at 3, 5, 7 and 10 days of life with a standardized protocol of measurements.
Results: Infants who did not develop CLD showed higher values of respiratory system dynamic compliance (Crsdyn) than the CLD group since the 5th day of life (p < 0.001). The values of lung resistance show a statistical significant difference between groups since the 7th day of life.
Conclusions: These findings indicate that, with a well standardized method of measurements, the value of Crsdyn can well be a good predictor and a sensible prognostic factors for CLD.
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