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Hydrogel coils in intracranial aneurysm treatment: a multicenter, prospective, randomized open-label trial.
J Neurosurg
January 2025
19Division of Medical Statistics, Division of Data Science, Foundation for Biomedical Research and Innovation at Kobe; and.
Objective: Studies have demonstrated the effectiveness of hydrogel-coated coils (HGCs) to achieve the composite endpoint of decreased recanalization rates and greater safety. Herein, the authors aimed to assess the true ability of second-generation HGCs to prevent recanalization.
Methods: This randomized controlled study, the HYBRID (Hydrocoil Versus Bare Platinum Coil in Recanalization Imaging Data) trial, comparing HGCs with bare platinum coils (BPCs), was conducted in 43 Japanese institutions.
Rebound Growth Following Temporary Discontinuation of BRAFi and MEKi in a Patient With Multifocal BRAFV600E-Mutant Primary Brain Tumor.
Neurology
February 2025
Department of Neurosurgery, Azienda USL Toscana Nord-ovest, Livorno Hospital.
Psilocybin-assisted massed cognitive processing therapy for chronic posttraumatic stress disorder: Protocol for an open-label pilot feasibility trial.
PLoS One
January 2025
Interventional Psychiatry Program, St. Michael's Hospital, Toronto, Ontario, Canada.
Background: Posttraumatic stress disorder (PTSD) affects 3.9% of the general population. While massed cognitive processing therapy (CPT) has demonstrated efficacy in treating chronic PTSD, a substantial proportion of patients still continue to meet PTSD criteria after treatment, highlighting the need for novel therapeutic approaches.
View Article and Find Full Text PDFNeural plasticity in early potters: Shape analysis and TMS-EEG co-registration trace the rise of a new motor skill.
PLoS One
January 2025
Department of Neuroscience, University of Padova, Padua, Italy.
In this study, we explored the biocultural mechanisms underlying ancient craft behaviours. Archaeological methods were integrated with neuroscience techniques to explore the impact on neuroplasticity resulting from the introduction of early pottery techniques. The advent of ceramic marked a profound change in the economy and socio-cultural dynamics of past societies.
View Article and Find Full Text PDFRecurrent glioblastoma in national guidelines on the diagnosis and treatment of gliomas: A matter of European practice variation.
Brain Spine
October 2024
Department of Neurosurgery, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.
Introduction: The optimal treatment for recurrent glioblastoma patients remains not well-defined in international guidelines. On top of that, the availability of national guidelines is uncharted.
Research Question: This study aimed to investigate the availability of national guidelines on the diagnosis and treatment of adult glioma throughout Europe, specifically focusing on recurrent glioblastoma.
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