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Scurvy: A call to maintain awareness.
Med Clin (Barc)
January 2025
Internal Medicine Department, Hospital Universitari Dexeus-Grupo Quirón Salud, Barcelona, Spain.
Military influences on the evolution of clinical trials throughout history.
Clin Trials
January 2025
Department of Urology, University of Rochester Medical Center, Rochester, NY, USA.
Clinical trials of drugs, procedures, and other therapies play a crucial role in advancing medical science by evaluating the safety, efficacy, and optimal use of medical interventions. The design and implementation of these trials have evolved significantly over time, reflecting advancements in medicine, ethics, and methodology. Early historical examples, such as King Nebuchadnezzar II's and his captives' dietary experiment and Ambroise Paré's treatment of gunshot wounds, laid some foundational principles of trial design.
View Article and Find Full Text PDFRapidly Enlarging Palatal Masses as a Novel Presentation of Scurvy.
Pediatr Blood Cancer
January 2025
University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Oral Manifestations of Vitamin C Deficiency in a Toddler.
J Dent Child (Chic)
September 2024
Department of Pediatric Hematology and Oncology, University of Illinois Chicago, Chicago, Ill., USA.
Vitamin C deficiency, colloquially known as scurvy, has become rare in modern times due to the widespread availability of ascorbic acid-rich foods. Despite this, it continues to be a concern in certain at-risk populations. The purpose of this report is to describe the case of a two-year-old girl who initially presented to a pediatric dental clinic with the chief complaint of hypertrophic gingiva and bleeding.
View Article and Find Full Text PDFScurvy in an 18-month-old child mimicking a clinical presentation of rickets.
Arch Pediatr
December 2024
General Pediatric Department, Versailles hospital, Le Chesnay, France.
Scurvy is now considered to be a rare disease in European countries, even among children, but it still exists. We report the case of an 18-month-old boy who was initially hospitalized for a walking disorder and ultimately diagnosed with scurvy. Radiographs were compatible with rickets, but biological analysis ruled out this diagnosis.
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