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Patients with end-stage renal disease face numerous physical, emotional, and financial burdens, necessitating palliative care (PC) interventions. This cross-sectional study assessed the problems and unmet needs of 129 patients under renal dialysis from 6 hospitals. Findings revealed that 64.
View Article and Find Full Text PDFIs vital exhaustion distinct? A meta-analytic investigation on the immediate nomological network of vital exhaustion.
J Health Psychol
January 2025
The University of Mississippi, School of Business Administration, USA.
A multitude of studies have supported that vital exhaustion is an important predictor of physical and psychological well-being, especially in the aftermath of adverse medical events; however, some authors have expressed that vital exhaustion may be repetitive with other popular constructs, namely burnout, fatigue, and depression. We resolve this tension by performing a meta-analysis of 74 sources on the immediate nomological network of vital exhaustion. Our results support that the relations of vital exhaustion with emotional exhaustion ( = 0.
View Article and Find Full Text PDFResponsiveness and clinical utility of PROMIS instruments in pediatric Crohn's disease: insights from a longitudinal study.
Front Pediatr
January 2025
Gastroenterology Unit, Pediatrics Department, Santa Maria University Hospital-CHLN, Academic Medical Centre of Lisbon, Lisbon, Portugal.
Background: Inflammatory bowel disease (IBD) may adversely affect physical, psychological, and social well-being. Integrating patient-reported outcomes (PROs) into clinical practice is crucial for comprehensive disease management.
Objective: To evaluate the responsiveness and clinical utility of Patient-Reported Outcomes Measurement Information System (PROMIS) instruments, compared with standard clinical assessment tools in pediatric CD patients.
Blood Lactate as a Metabolic Biomarker of Anaerobic Vocal Capacity: A Pilot Study.
J Voice
January 2025
Department of Speech, Language, and Hearing Sciences, Auburn University, Auburn, AL.
Purpose: Blood lactate concentration is commonly used to assess metabolic demand and skeletal muscle training response. The objective of the pilot study was to investigate if a change in blood lactate was detectable in an anaerobically designed vocal demand task vocal capacity anaerobic task (VCAT) and determine if the developed vocal demand task may assess the anaerobic capacity of the voice musculature, like anaerobic power tests commonly used in applied exercise science.
Methods: A prospective repeated measures study quantified blood lactate concentration preVCAT and postVCAT in vocally healthy adults.
Ex vivo electrophysiological evaluation of peripheral nerve functioning following exposition of adult mice to the organophosphorus pesticide chlormephos.
Environ Toxicol Pharmacol
January 2025
Université Paris-Saclay, CEA, Institut des sciences du vivant Frédéric Joliot, Département Médicaments et Technologies pour la Santé (DMTS), Service d'Ingénierie Moléculaire pour la Santé (SIMoS), EMR CNRS/CEA 9004, 91191 Gif-sur-Yvette, France. Electronic address:
The organophosphorus pesticide chlormephos was tested for its potential peripheral neurotoxicity by analyzing the diphasic compound action potential (CAP) of sciatic nerves isolated from adult mice chronically exposed to a sub-lethal dose of this pesticide, compared with control age-matched animals being only exposed to the vehicle. No significant modification was detected between chlormephos-exposed and control groups in their nerve responsiveness to stimulus. Furthermore, similar values of CAP kinetic variables were obtained from the two mouse groups.
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