Background: Since people with chromosome 22q11 deletion (CATCH 22 syndrome) have unexpectedly high incidence of major psychosis it has been suggested that 22q area might be involved in the pathogenesis of schizophrenia and bipolar disorders.
Method: A single case report.
Results: A 32-year-old male patient with CATCH 22 syndrome and schizophrenia had extensive midline anomalies of the brain in the regions relevant to psychotic disorders.
Conclusions: 22q11-dependent abnormalities in the midline structures of the brain may cause dysfunction in the limbic system and interfere with the interhemispheric information exchange thus predisposing people with CATCH 22 syndrome to psychotic disorders.
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http://dx.doi.org/10.1192/bjp.172.6.518 | DOI Listing |
J Hip Preserv Surg
December 2024
Hip and Knee Adult Reconstruction Department, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra, Calzada México-Xochimilco No. 289 Colonia Arenal de Guadalupe Delegación, Tlalpan C.P., Ciudad de México 14389, México.
Femoroacetabular impingement syndrome (FAIS) is a common condition of the hip that can cause significant damage to the joint, leading to degeneration and osteoarthritis. FAIS constitutes an abnormal and dynamic contact between the femoral head-neck junction and the acetabular rim, resulting from altered bone morphology at one or both sites. Repetitive trauma at the site of impingement generates progressive damage to the acetabular labrum, chondrolabral junction, and articular cartilage.
View Article and Find Full Text PDFJ Med Genet
January 2025
Service de Génétique, Centre Hospitalier Régional Universitaire de Tours, Tours, France
Background: Aarskog-Scott syndrome (AAS) is a rare condition with multiple congenital anomalies, caused by hemizygote variants in the gene. Its description was based mostly on old case reports, in whom a molecular diagnosis was not always available, or on small series. The aim of this study was to better delineate the phenotype and the natural history of AAS and to provide clues for the diagnosis and the management of the patients.
View Article and Find Full Text PDFCureus
November 2024
Department of Physical Therapy for Musculoskeletal Disorders, Faculty of Physical Therapy, Beni Suef University, Beni Suef, EGY.
Background The coronavirus disease 2019 (COVID-19) was an expanding pandemic caused by a new strain of the coronavirus family known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). No previous studies have examined the impact of COVID-19 pandemic on physical therapy practice in Egypt. Objectives This study aimed to assess the impact of COVID-19 pandemic on physical therapy clinical practice in Egypt five months after the pandemic declaration.
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