Leiomyosarcoma is an uncommon malignant tumour of the pancreas. Many retroperitoneal leiomyosarcomas grow silently and are extremely large when diagnosed. We report a 45 year old lady who presented with abdominal lump and haemoptysis. Ultrasound guided biopsy of the mass revealed a pancreatic leiomyosarcoma. The patient had lung metastasis and received chemotherapy. She is alive with disease at last followup.
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World J Gastrointest Surg
November 2024
Department of Hepatobiliary and Pancreatic Surgery, Lishui Municipal Central Hospital, Lishui 323000, Zhejiang Province, China.
Background: Primary hepatic leiomyosarcoma (PHL) is a rare malignant tumor and has non-specific clinical manifestations and imaging characteristics, making preoperative diagnosis challenging. Here, we report a case of PHL presenting primarily with fever, with computed tomography imaging showing a thick-walled hepatic lesion with low-density areas, resembling liver abscess.
Case Summary: The patient was a 34-year-old woman who presented with right upper abdominal pain and fever over 4 days before admission.
Cureus
October 2024
Oncology/Radiation Oncology, Tawam Hospital, Al Ain, ARE.
This case report describes the diagnosis, treatment, and progression of a 50-year-old male patient diagnosed with stage IV pancreatic leiomyosarcoma with metastases to the liver, lungs, and brain, representing the only case involving both the pancreas and brain documented in the hospital registry with a histopathological diagnosis of leiomyosarcoma. The patient initially presented with chronic abdominal pain, constipation, and weight loss, and subsequent CT scans revealed a large pancreatic mass with metastases to the liver, lungs, and brain. A biopsy confirmed the diagnosis of leiomyosarcoma, and the patient underwent eight cycles of palliative chemotherapy with cisplatin and docetaxel, along with palliative radiotherapy targeting the brain metastases.
View Article and Find Full Text PDFJ Vasc Interv Radiol
November 2024
Department of Radiology, Division of Interventional Radiology, Massachusetts General Hospital Boston & Harvard Medical School, Boston, Massachusetts.
Purpose: To evaluate oncological outcomes, abscopal effect, and adverse events (AEs) of pulsed electrical field (PEF) ablation of tumors in the chest, abdomen, and pelvis.
Materials And Methods: PEF ablations performed at an academic medical center between May 2023 and January 2024 were retrospectively analyzed. Eleven patients (4 males and 7 females; age, 58 years ± 19) underwent 11 PEF sessions targeting 13 tumors (lung metastasis from solitary fibrous tumor [n = 3] and colorectal carcinoma (CA) [n = 1], osteosarcoma pleural metastases [n = 2], hepatocellular CA [n = 2], liver metastasis from colorectal CA [n = 1] and leiomyosarcoma [n = 1], metastatic melanoma to the pancreas [n = 1], metastatic retroperitoneal lymph node from endometrial CA [n = 1], and recurrence of endometrial CA in the vaginal cuff [n = 1]) with the goal of complete coverage (n = 11/13) or debulking (n = 2/13).
Mod Pathol
November 2024
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address:
Hepatobiliary Pancreat Dis Int
September 2024
Division of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
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