The authors report the case of a 22-year-old female suffering from thigh pain for 5 months. The first diagnosis considered was circumscribed myositis ossificans but the duration of symptoms and the radiological aspect mimicking some malignant features led to consider parosteal sarcoma as a possible diagnosis. Surgical resection was therefore requested and histological analysis confirmed the diagnosis of circumscribed myositis ossificans. This case emphasizes the difficulty in differentiating circumscribed myositis ossificans from a slowly growing tumor as both can be associated with increasing pain and a malignant radiological aspect. A surgical approach is therefore frequently necessary for definitive diagnosis and treatment.
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Neuromuscul Disord
December 2024
Center for Gene Therapy, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA; Department of Pediatrics and Neurology, Nationwide Children's Hospital and The Ohio State University, Columbus, OH, USA; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Localized painful nodules associated with focal myositis have been previously documented, either as isolated occurrences or in conjunction with systemic illnesses, such as polymyositis [1-4]. These nodules typically manifest over the course of 2-8 weeks and exhibit histological features consistent with inflammatory myositis. Here we present a unique case of a patient with a history of myasthenia gravis, who experienced exacerbation of myasthenic symptoms, accompanied by the development of palpable, tender nodules on her thighs and proximal weakness.
View Article and Find Full Text PDFRadiol Case Rep
December 2024
Pediatric Radiology Department, Children's Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Circumscribed myositis ossificans is a benign process of focal heterotopic ossification of the soft tissues, occurring in young subjects, usually following trauma. We report a case of a 15-year-old patient who suffered a direct trauma to the thigh during a soccer match, and developed a hard mass in the anterior face of the thigh. The patient was diagnosed with myositis ossificans secondary to trauma.
View Article and Find Full Text PDFFront Pediatr
December 2023
Department of Pediatric Orthopedic Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Introduction: Circumscribed or pseudomalignant myositis ossificans (MO) is a rare and benign condition characterized by heterotopic bone formation in soft tissues. The clinical presentation of MO, imaging investigations, histological findings, and treatment strategies are unclear, especially in the pediatric population.
Materials And Methods: A literature search was conducted in PubMed, Scopus, and Google Scholar electronic databases to identify original articles and reviews in English or French of traumatic and non-traumatic MO.
Int J Surg Pathol
August 2024
Pathology, La Paz University Hospital, Madrid, Spain.
Introduction: A soft tissue aneurysmal bone cyst is an extremely rare tumor. The objective of the article is to present the clinical, radiological, and histopathological features of a very unusual neoplasm of soft tissues.
Case Report: A 13-year-old male patient presented a painful, mobile, and rapidly growing mass on the posteromedial aspect of his left knee.
Radiol Case Rep
April 2023
Mother and Child Imaging Department - HER - Ibn Sina Hospital, Mohammed V University in Rabat, Rabat, Morocco.
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