Six cases of nitrate poisoning in cattle are reported. The fact that the symptoms were highly acute and appeared as rapidly as within a few hours after feeding, was a striking feature in dairy cows. Deaths occurred among yearlings without the stock owners having previously noticed any changes. In those cases in which post-mortem studies were done, characteristic changes were not observed, with the exception of engorgement of the lungs with blood or paleness of the mucosae. Nitrate levels were found to vary markedly within a single lot of roughage. Early administration of methylene blue to reduce methaemoglobin and treatment with hypertensive agents may be life-saving.
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J Vet Diagn Invest
January 2025
Large Animal Clinical Sciences, Western College of Veterinary Medicine, Saskatoon, Saskatchewan, Canada.
An apparent outbreak of fenugreek forage toxicosis occurred in a beef cattle herd near Moose Jaw, Saskatchewan in February-May 2022. The herd had consumed fenugreek hay from late fall to early winter. Clinical signs included various degrees of weakness, ataxia, knuckling, walking on hocks, and recumbency.
View Article and Find Full Text PDFSci Rep
December 2024
Animal Biotechnology Division, National Institute of Animal Science, Rural Development Administration, Wanju, Republic of Korea.
Small intestinal organoids are similar to actual small intestines in structure and function and can be used in various fields, such as nutrition, disease, and toxicity research. However, the basal-out type is difficult to homogenize because of the diversity of cell sizes and types, and the Matrigel-based culture conditions. Contrastingly, the apical-out form of small intestinal organoids is relatively uniform and easy to manipulate without Matrigel.
View Article and Find Full Text PDFToxins (Basel)
November 2024
Immunoassays/Immunosensors Lab, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR "Demokritos", 15341 Aghia Paraskevi, Greece.
Aflatoxin M1 (AFM1) exposure through dairy products is associated with adverse health effects, including hepatotoxicity and carcinogenicity. Therefore, the AFM1 presence in milk and dairy products is strictly regulated. In this context, the current work focuses on the investigation of different competitive enzyme immunoassay configurations for the determination of AFM1 in milk with high sensitivity and short assay duration.
View Article and Find Full Text PDFBiol Trace Elem Res
December 2024
Agricultural Research Service-Poisonous Plant Research Lab, USDA, Logan, UT, 84341, USA.
Supranutritional Se supplementation may improve immune responses in beef cattle. Immunity is compromised in beef cattle during the periparturient period. This study aims to determine the best time during pregnancy to supplement beef cows with Se-yeast to optimize humoral immunity at parturition.
View Article and Find Full Text PDFEnviron Monit Assess
December 2024
Department of Food Safety and Hygiene, School of Health, Fasa University of Medical Sciences, Fasa, Iran.
Milk and dairy products are an important source of essential nutrients for human health. However, contamination of these foods poses a significant public health concern. In this study, risk assessment of aflatoxin M1 (AFM1) exposure associated with the consumption of traditional milk and dairy products in Fasa, Fars Province, Iran, was carried out.
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