Ethyl 3-chloro-6-(4-chlorophenyl)-pyridazine-4-carboxylate [VII] was cyclized with some nucleophilic reagents (hydrazine hydrate or N-monosubstituted hydrazines) to the new derivatives of pyrazolo[3,4-c]pyridazine [IXa-d]. The structures of the novel compounds were confirmed by elemental and spectral analyses. The effect of several synthesized derivatives on the central nervous system was studied.

Download full-text PDF

Source

Publication Analysis

Top Keywords

synthesis pharmacological
4
pharmacological screening
4
screening pyrazolo[34-c]pyridazine
4
pyrazolo[34-c]pyridazine derivatives
4
derivatives ethyl
4
ethyl 3-chloro-6-4-chlorophenyl-pyridazine-4-carboxylate
4
3-chloro-6-4-chlorophenyl-pyridazine-4-carboxylate [vii]
4
[vii] cyclized
4
cyclized nucleophilic
4
nucleophilic reagents
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!